PURPOSE To evaluate the prevalence of pterygium and its determinants in the underserved, rural population of Iran. METHODS In this cross-sectional study of 3851 selected individuals, 86.5% participated in the study, and the prevalence of pterygium was evaluated in 3312 participants. A number of villages were selected from the north and south of Iran using multistage cluster sampling. Pterygiu...

OBJECTIVE To report the clinical characteristics and treatment of subjects with incomitant esotropia following unilateral pterygium excision. METHODS A retrospective review of 6 consecutive patients who developed incomitant esotropia, limited abduction, and diplopia following unilateral pterygium excision surgery. RESULTS The mean preoperative deviation was 6 prism diopters (PD) (range, 0-2...

PURPOSE To investigate the role of postoperative topical 0.05% cyclosporine A (CsA) eye drops (Restasis(®), Allergan Pharmaceutical) in the prevention of recurrence among patients with primary pterygium treated with bare-sclera technique. METHODS In this prospective randomized controlled study, 36 eyes (34 patients) with primary pterygium were randomized into two groups: Group I comprised 18 ...

Although numerous population-based studies have reported the prevalences and risk factors for pterygium, information regarding the incidence of pterygium is scarce. This population-based cohort study aimed to evaluate the South Korean incidence and prevalence of pterygium. We retrospectively obtained data from a nationally representative sample of 1,116,364 South Koreans in the Korea National H...

PURPOSE Urokinase-type plasminogen activator (uPA) is a protease involved in tissue remodeling and cell migration. Little is known about the expression of uPA in pterygium. The purpose of this study was to investigate the expression of uPA mRNA and activities in various stages of surgically excised pterygia specimens and cultured pterygium fibroblasts and to compare them with normal conjunctiva...

We aimed to compare the recurrence rate following primary pterygium surgery using two different techniques, i.e. simple conjunctival closure (SCC) and rotational conjunctival flap (RCF). Postoperative discomfort and complications were also investigated in these patients.

AIM To study the efficacy and safety of amniotic membrane graft as an adjunctive therapy after removal of primary pterygium, and to compare the clinical outcome with conjunctival autograft and topical mitomycin C. METHODS 80 eyes of 71 patients with primary pterygia were treated with excision followed by amniotic membrane graft. The result was compared retrospectively with 56 eyes of 50 patie...

PURPOSE To determine whether oral doxycycline treatment reduces pterygium lesions. DESIGN Double blind, randomized, placebo controlled clinical trial. PARTICIPANTS 98 adult patients with primary pterygium. METHODS Patients were randomly assigned to receive 100 mg oral doxycycline twice a day (49 subjects), or placebo (49 subjects), for 30 days. Photographs of the lesion were taken at the ...

PURPOSE To evaluate the efficacy of intralesional bevacizumab injection in decreasing size of pterygium. METHODS Seventeen patients with pterygium (14 with primary and 3 with recurrent pterygium) received intralesional injections of bevacizumab (2.5 mg/0.1 mL). Digital photographs were analyzed by image analysis software to determine the change of corneal involvement as a percentage of the to...