We have previously shown that lipoma preferred partner (LPP) mediates TGFβ-induced breast cancer cell migration and invasion. Herein, we demonstrate that diminished LPP expression reduces circulating tumour cell numbers, impairs cancer cell extravasation and diminishes lung metastasis. LPP localizes to invadopodia, along with Tks5/actin, at sites of matrix degradation and at the tips of extrava...

Data Envelopment Analysis is based on linear programming problems (LPP) in order to find the efficiency of Decision Making Units (DMUs). This process can be computationally intense, as a LPP has to be run for each unit. Besides, a typical DEA LPP has a large number of redundant constraints concerning the inefficient DMUs. That results in degenerate LPPs and in some cases, multiple efficient sol...

BACKGROUND Frontal fibrosing alopecia (FFA) is an acquired scarring alopecia currently considered a clinical variant of lichen planopilaris (LPP). Our purpose was to examine the clinicopathological features of FFA. In addition, we investigated the similarities and differences between FFA and LPP. METHODS Biopsies from the scalp lesions of eight patients with FFA and eight patients with LPP we...

The LPP gene is the preferred translocation partner of the HMGIC gene in a subclass of human benign mesenchymal tumors known as lipomas. Here we have characterized the LPP gene product that shares 41% of sequence identity with the focal adhesion protein zyxin. LPP localizes in focal adhesions as well as in cell-to-cell contacts, and it binds VASP, a protein implicated in the control of actin or...

Purpose of the study: The subject consideration is actual actions clothing brands in pro-environmental areas. main purpose article to describe sustainability and behavior companies selling private label clothing.
 Methodology: This was prepared with use analyses LPP S.A. reports, rankings environmentally conscious other articles.
 Findings Sustainable development influencing increased...

In this paper, we propose a mathematical model in stochastic dynamic optimization form to determine the optimal strategy for an integrated single product inventory control problem and supplier selection problem where the demand and purchasing cost parameters are random. For each time period, by using the proposed model, we decide the optimal supplier and calculate the optimal product volume pur...

Supplier selection is an important issue in supply chain management. In recent years, determining the best supplier in the supply chain has become a key strategic consideration. However, these decisions usually involve several objectives or criteria, and it is often necessary to compromise among possibly conflicting factors. Thus, the multiple criteria decision making (MCDM) becomes a useful ap...

This paper presents the development of a model based decision support system with a case study on solving the supplier selection problem in a chemical processing industry. For the evaluation and selection of supplier, the analytical hierarchy process (AHP) and grey relational analysis (GRA) were used. The intention of the study is to propose an appropriate platform for process industries in ...

We consider supplier development within a supply chain consisting of a single manufacturer and a single supplier. Because investments in supplier development are usually relationship-specific, safeguard mechanisms against the hazards of partner opportunism have to be installed. Here, formal contracts are considered as the primary measure to safeguard investments. However, formal contracts entai...

The changing economic conditions have challenged many organizations to search for more efficient and effective ways to manage their supply chain. During recent years supplier selection decisions have received considerable attention in the supply chain management (SCM) literature. There are four major decisions that are related to the supplier selection process: what product or services to order...