نتایج جستجو برای: proinflammatory markers
تعداد نتایج: 245531 فیلتر نتایج به سال:
INTRODUCTION Anticoagulant therapy attracts much attention for the treatment of severe sepsis since recent studies have revealed that some anticoagulants have the ability to regulate the inflammatory response. The purpose of this study was to examine whether danaparoid sodium (DA) is effective for the treatment of organ dysfunction in sepsis. METHODS Sixty-four Wistar rats were intravenously ...
Abstract Oral squamous cell carcinoma (OSCC) is the most common malignant tumor of oral mucosa. Currently, diagnosis cancer based on clinical examination and histopathological analysis. Numerous potential biomarkers have been suggested for diagnosis, but results are contradictory. A great achievement could be identification that indicate early stage progression OSCC. Saliva an easy to obtain bi...
Background Regulatory T cells (Treg) are abundant in the inflamed joints of children with JIA. However the high number of Treg is not able to control the inflammation within the joint, suggesting a shortcoming of their regulatory function. It has been suggested that Treg can develop a proinflammatory profile that is specifically related to the local pro-inflammatory response. In this study we i...
Metabolic syndrome (MetS) is a primary risk factor for cardiovascular disease and is associated with a proinflammatory state. Here, we assessed the contribution of inflammatory and oxidative stress markers towards prediction of MetS. A total of 2316 individuals were recruited in Phase I of the Indian Atherosclerosis Research Study (IARS). Modified ATPIII guidelines were used for classification ...
aim: was to assess the effects of ramadan observance upon repeated sprints and associated inflammatory and oxidative stress responses. methods: ten young trained boxers were tested during a control period (c), at the end of the first week (r-1), and during the fourth week of ramadan observance (r-4). on each occasion, they performed three vertical jumps, 10 x 6 s repeated sprints on a cycle erg...
HIV-infected slow progressors (SP) represent a heterogeneous group of subjects who spontaneously control HIV infection without treatment for several years while showing moderate signs of disease progression. Under conditions that remain poorly understood, a subgroup of these subjects experience failure of spontaneous immunological and virological control. Here we determined the frequency of SP ...
Spinal glial and proinflammatory cytokine actions are strongly implicated in pathological pain. Spinal administration of the anti-inflammatory cytokine interleukin (IL)-10 abolishes pathological pain and suppresses proinflammatory IL-1β and tumor necrosis factor alpha (TNF-α). Drugs that bind the cannabinoid type-2 receptor (CB(2)R) expressed on spinal glia reduce mechanical hypersensitivity. T...
Cysticidal treatment of neurocysticercosis, an infection of humans and pig brains with Taenia solium, results in an early inflammatory response directed to cysts causing seizures and focal neurological manifestations. Treatment-induced pericystic inflammation and its association with blood brain barrier (BBB) dysfunction, as determined by Evans blue (EB) extravasation, was studied in infected u...
OBJECTIVE Apolipoprotein E (apoE) exerts potent antiinflammatory effects. Here, we investigated the effect of apoE on the functional phenotype of macrophages. METHODS AND RESULTS Human apoE receptors very-low-density lipoprotein receptor (VLDL-R) and apoE receptor-2 (apoER2) were stably expressed in RAW264.7 mouse macrophages. In these cells, apoE downregulated markers of the proinflammatory ...
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