Biosynthesis of Silver Nanoparticles Using Hydroethanolic Extract Cucurbita pepo L. Fruit and Their Anti-proliferative Apoptotic Activity Against Breast Cancer Cell Line (MCF-7)

Background: Nicotine can induce sub fertility and infertility in females. The aim of this study was to determine the effect of nicotine on follicular cells proliferative activity in mouse ovary. Materials and Methods: Female adult NMRI mice were divided into two groups. Animals in control group received vehicle, however in experimental group, animals were treated with 0.4mg/kg of nicotine for 1...

I. Causative Agent and Disease Reports of abnormal proliferation of tissues in marine decapod crustaceans have been extremely rare. There have been less than a dozen cases in the literature of which only four have shown convincing evidence of cancer. Cancers or neoplasms are growths of abnormal cells that proliferate uncontrollably and have no useful function as opposed to cells that are normal...

Objective(s) Studies have shown that morphine, in addition to its analgesic properties, has several effects on cell proliferation and apoptosis. There is also evidence that opioid receptors are present on chondrocytes. Our main objective in the present study was to investigate the effects of morphine on rat femur growth cartilage. Materials and Methods This research was carried out on 18 4-we...

introduction : laser therapy prevents complications of proliferative diabetic retinopathy (pdr), central retinal vein occlusion (crvo) and branch retinal vein occlusion (brvr), but its effect on visual acuity is controversial. this study evaluated the effect of laser on visual acuity in these patients. materials and methods: this interventional study conducted before–after treatment and evaluat...

in many acute leukemias, normal differentiation does not occur. however, in many cell lines derived from hematologic malignancies, differentiation or programmed cell death (apoptosis) can be induced by variety of agents including: vitamin analogs, demethylating agents, cyclic amp analogs and anti-proliferative agents. to the best of our knowledge there has been not any study specifically to ana...

Aims: The objective of the study was to determine clinical utility different ratios serum lipid and apolipoprotein as predictive markers for diabetic retinopathy (DR). Methodology: In this case control study, participants were divided in four groups, normal controls, non-proliferative (NPDR) proliferative (PDR). Staging done based on fundoscopy by an ophthalmologist. A fasting venous blood assa...

We analyzed gene expression in rat anti-Thy1 antibody-induced glomerulonephritis by using the cDNA microarray method. Ninety-seven genes that differed by more than 1.5-fold intensity in comparison with the controls were selected. Cluster analysis showed that the expression of genes associated with inflammation reached maximum levels at 24 h, while genes involved in the development of fibrosis i...

PURPOSE Ablating and cutting vitreoretinal membranes using a 193-nm excimer laser-based microsurgical system. METHODS A 193-nm microsurgical system enables delivery of the beam into a fluid medium to cut preretinal and subretinal membranes. Two patients with proliferative diabetic retinopathy and one patient with proliferative vitreoretinopathy were treated with this new device. RESULTS Gen...