We describe a system, Prompt, used to design physical systems. Prompt employs a multi-level approach to design. When simple constraint propagation over prototypes [Adda fails, Prompt can significantly modify prototypes by reasoning about their structure and physics. Prompt derives the behavior of a prototype from its structure using knowledge of physics stored in a Graph of Models. It then uses...

In ee and in hadron-hadron reactions at collider energies, prompt photons are observed and their cross sections are measured only if the photons are relatively isolated in phase space. Isolation is required to reduce various hadronic backgrounds including those from the electromagnetic decay of mesons, e.g., π → 2γ. The essence of isolation is that a cone of half-angle δ is drawn about the dire...

We report quantitative measurements of OH vibrational prompt emission in comets C/1999 H1 (Lee) and C/2001 A2 (LINEAR) based on high-dispersion infrared spectra acquired at the Keck Observatory atop Mauna Kea, Hawaii. Effective g-factors for four OH lines near 3046 cm 1 (in the 1–0 band) were obtained from simultaneous detections of OH and H2O. The measured spatial distribution of this OH ‘‘qua...

OBJECTIVE Ghrelin, a gut-brain peptide involved in the control of energy homeostasis, affects antero-pituitary and gastro-entero-pancreatic (GEP) hormone secretion in healthy subjects. We aimed to verify whether such hormonal responses are retained in acromegaly, a disease characterized by high GH, subnormal ghrelin and abnormal GEP hormone levels. DESIGN AND METHODS The effect of ghrelin (3....

The octaoligoisonucleotide (isoT)2(isoG)4(isoT)2 (I), consisting of isonucleoside units 6'-O-allyl-4'-deoxy-4'-(nucleobase)-2',5'-anhydro-L-mannitol, was synthesized by the phosphotriester approach in solution phase. Based on CD spectra and capillary electrophoresis, it was confirmed that iso-oligomer I could form a parallel intermolecular G-quadruplex structure. K+, Na+ and Li+ can prompt the ...

We report the case of a young boy being considered for pituitary surgery because of pituitary enlargement found during assessment of growth delay. There was no goitre but he was hypothyroid clinically and biochemically. The finding of an elevated TSH suggested primary thyroid disease with thyrotroph hyperplasia. Treatment with L-thyroxine resulted in prompt resolution of his pituitary enlargeme...

Prompt deliquescence and efflorescence of aerosol nanoparticles G. Biskos, D. Paulsen, L. M. Russell, P. R. Buseck, and S. T. Martin Division of Engineering and Applied Sciences, Harvard University, Cambridge, MA 02138, USA Scripps Institution of Oceanography, University of California San Diego, La Jolla, CA 92093, USA Departments of Geological Sciences and Chemistry/Biochemistry, Arizona State...

A single step etch/primer that can be used for bonding orthodontic brackets with virtually any light polymerized resin-based composite bracket adhesive material that has been introduced. Clinical trials have shown it to be especially useful in re-bonding detached metallic or ceramic brackets, and for bonding brackets to fluorosed enamel. This technique report describes the PROMPT L-POP* system ...