BACKGROUND Prostate-specific antigen (PSA) screening is growing in popularity in China, but its impact on biopsy characteristics and outcomes are poorly understood. OBJECTIVE Our objective was to characterize prostate biopsy outcomes and trends in Chinese men over a 10-year period, since the increasing use of PSA tests. METHODS All men (n = 1,650) who underwent prostate biopsy for PCa at Hu...

Objective To explore the effect of 3-dimensional (3D) printing-assisted cognitive fusion on improvement of the positive rate in prostate biopsy. Methods From August to December 2014, 16 patients with suspected prostatic lesions detected by multiparametric magnetic resonance imaging (MRI) were included. Targeted prostate biopsy was performed with the use of prostate 3D reconstruction modeling,...

This study investigates the detection rate of nonpalpable, isoechoic occult prostate malignancy using a stereotactic transperineal prostate biopsy (STPB) technique in patients with a previously negative transrectal ultrasound-guided prostate biopsy.

OBJECTIVE To investigate whether core length is a significant biopsy parameter in the detection of prostate cancer. MATERIAL AND METHODS We retrospectively analyzed pathology reports of the specimens of 188 patients diagnosed with prostate cancer who had undergone initial transrectal ultrasound (TRUS) guided prostate biopsy, and compared biopsy core lengths of the patients with, and without p...

BACKGROUND The aim of our study was to identify the optimal predictor of prostate cancer among several prostate-specific antigen (PSA) derivatives in repeat prostate biopsy. METHODS We retrospectively assessed the repeat prostate biopsy specimens, obtained between 1999 and 2008, of 212 patients with a total PSA (tPSA) of 4-10 ng/ml and normal digital rectal examination. Using a receiver opera...

PURPOSE The human kallikrein-2 (hK2) protein and two single nucleotide polymorphism (SNPs) (rs2664155, rs198977) of the gene are associated with prostate cancer risk. We examined whether hK2 protein and gene SNPs predict prostate cancer at the time of repeat biopsy. METHODS We prospectively offered a repeat biopsy to men with a negative prostate biopsy performed for a PSA >4.0 ng/mL or abnorm...

Abstract Introduction LIKERT 4 and 5 lesions picked up on MRI prostate have a high chance of picking grade volume cancer so they under biopsy. It is quite challenging to decide whether biopsy pure 3 lesions. In our retrospective review 500 scan we looked for correlation between the risk finding after Materials Methods Pre-biopsy Multi parametric was done in cases reported by two consultant radi...

BACKGROUND Prostate-specific antigen (PSA) is widely used to detect prostate cancer. The low positive predictive value of elevated PSA results in large numbers of unnecessary prostate biopsies. We set out to determine whether a multivariable model including four kallikrein forms (total, free, and intact PSA, and human kallikrein 2 (hK2)) could predict prostate biopsy outcome in previously unscr...

MRI-targeted biopsy is a promising technique that offers an improved detection of clinically significant prostate cancer over standard non-targeted biopsy. It is established that prostate MRI is of use in both the primary and repeat biopsy setting for the detection of significant prostate cancer. There are three approaches to targeting biopsies to areas of interest seen on prostate MRI. They ea...

The technique of the standard transrectal ultrasound (TRUS)-guided prostate biopsy was initially demonstrated in the pre-PSA era, the late 1980s when prostate cancer was mostly a high volume, palpable disease.[2] Apart from the addition of extra cores in an extended biopsy technique, the technique remains essentially the same; systematic and nontargeted. It samples only 0.04% of an average size...