Low or absent expression of the cyclin-dependent kinase inhibitor p27(Kip1) serves as an excellent malignant marker for prostate and other human cancers. The level of p27(Kip1) is regulated primarily by the ubiquitin E3 ligase SCF(SKP2) through ubiquitin-dependent proteolysis. Expression of the F-box protein SKP2 is inversely correlated with p27 in many cancers. To determine the role of SCF(SKP...

Low or absent expression of the cyclin-dependent kinase inhibitor p27 serves as an excellent malignant marker for prostate and other human cancers. The level of p27 is regulated primarily by the ubiquitin E3 ligase SCF through ubiquitin-dependent proteolysis. Expression of the F-box protein SKP2 is inversely correlated with p27 in many cancers. To determine the role of SCF in proliferation and ...

The giant anteater (Myrmecophaga tridactyla) is a vulnerable species from Central and South America, considered possibly extinct in Belize, Guatemala, El Salvador, Uruguay. Due to the species’ conservation reproductive importance, this research aimed characterize morphology, histochemical, immunohistochemical, ultrastructural feature of prostate gland. For this, we collected 11 glands performed...

Benign Prostate Hypertrophy is a disease of elderly males. Modern pathy has described many causes and treatment of the disease. Unani pathy too has description of disease and the treatment in its resource books. The description is in different ways. At some places, it has been described in symptomatic form while at other places it has been considered as a disease. The disease has different name...

Benign Prostate Hypertrophy is a disease of elderly males. Modern pathy has described many causes and treatment of the disease. Unani pathy too has description of disease and the treatment in its resource books. The description is in different ways. At some places, it has been described in symptomatic form while at other places it has been considered as a disease. The disease has different name...

A growing body of literature has established the anabolic benefi ts of testosterone (T) therapy in hypogonadal men. However, there remains a paucity of data regarding the risks of exogenous androgen use in older men and the potential for adverse effects on the prostate gland. Whether T therapy in older, hypogonadal men might worsen lower urinary tract symptoms or exacerbate, unmask, or even inc...