background: the aim of this study was to evaluate over expression of epidermal growth factor receptor (egfr) gene in localized prostate cancers and determine its relation with clinical and pathological factors affecting the progression of the disease. methods: in the tissue samples of the patients with prostate cancer undergoing radical prostatectomy, egfr expression was evaluated by immunohist...

BACKGROUND Hypo-fractionated external beam radiotherapy with narrow CTV-PTV margins is increasingly applied for prostate cancer. This demands a precise target definition and knowledge on target location and extension during treatment. It is unclear how increase in fraction size affects changes in prostate volume during treatment. Our aim was to study prostate volume changes during extreme hypo-...

Prostate cancer is an important health problem. More than 40 000 incident cases of prostate cancer and more than 10 000 prostate cancer related deaths occur each year in the United Kingdom. Prevention, detection, and treatment of localized prostate cancer remain controversial. Although screening for prostate cancer with serum prostate specific antigen (PSA) testing is not approved in the UK, in...

we assessed the lower urinary tract symptoms (luts) in prostatic cancer patients and investigated the sensitivity and specificity of international prostate symptom score (ipss) in the screening of these patients. a total number of 132 prostatic cancer patients as the case group who were confirmed by the pathologists and 101 noncancerous men as the control group, aged 50 or older, responded to a...

tgiflx, a homoproteins cluster member located on the x chromosome, has a critical role in male reproduction and prostate development. previous studies have shown the erratic expression of tgiflx gene in a large proportion of prostate tumors. however tgiflx function in prostate development remains unknown. the purpose of this study was to evaluate the consequences of tgiflx expression on prostat...

background and aims: epigallocatechin-3-gallate (egcg) is a polyphenolic compound from green tea, which its anticancer effects on many types of cancers have been confirmed, but the molecular mechanism by which egcg induces apoptosis remains unknown. the aim of the present study was to investigate anti-proliferative properties and apoptotic signaling pathway of egcg on pc3 human prostate cancer ...

The treatment for prostate abscesses includes a combination of antimicrobial therapy and surgical drainage of the abscess cavity. There is a lack of published cases involving treatment options for a prostate abscess after a failed transurethral resection of the prostate. This is a case report describing a successful salvage treatment after a failed attempt at abscess drainage by a transurethral...

Prostate cancer is the most common solid malignancy in men, with 32,000 deaths annually. Piperine, a major alkaloid constituent of black pepper, has previously been reported to have anti-cancer activity in variety of cancer cell lines. The effect of piperine against prostate cancer is not currently known. Therefore, in this study, we investigated the anti-tumor mechanisms of piperine on androge...

Prostate cancer is a prevalent problem in male healthcare. The previous decades have witnessed some significant improvements the knowledge of aetiology and pathology, as well practice screening, treatment, follow-up disease. A downstaging at time diagnosis increase survival were vivid with advancements, albeit screening disease using regular prostate specific antigen measurements was previously...