نتایج جستجو برای: protease 2a 2apro

تعداد نتایج: 69407  

Journal: :Bulletin of The Chemical Society of Ethiopia 2021

Copper-based oxide glass-ceramic was successfully synthesized through the single-step melt annealing technique. Synthesized glass-ceramics characterized using X-ray diffraction (XRD) and scanning electron microscopy (SEM) supported with energy dispersive (EDX) mapping. Pyrazolo[1,5-a]pyrimidines 5a-f were via reaction of 5-amino-1H-pyrazole-4-carboxamide (1) enaminones 2a-f in presence catalyst...

Journal: :Antiviral therapy 2011
Amy K Sheaffer Min S Lee Dennis Hernandez Susan Chaniewski Fei Yu Paul Falk Jacques Friborg Guangzhi Zhai Fiona McPhee

BACKGROUND To support clinical development of HCV non-structural protein (NS) 3 protease inhibitors (PIs), phenotypic monitoring of patient isolates is a prerequisite for understanding the emergence of resistance. HCV isolates typically fail to replicate in cell culture, necessitating the use of alternative phenotyping methods. METHODS An NS3 protease chimeric replicon system was developed to...

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