Aim Gene assessment of pancreatic adenocarcinoma disease via protein-protein interaction (PPI) Network Analysis. Background Diagnosis, especially early detection of pancreatic adenocarcinoma as a lethal disease implies more investigation. PPI Network Analysis is a suitable tool to discover new aspects of molecular mechanism of diseases. Methods In the present study the related genes to panc...

Proteins are linear polymers built from 20 building blocks called amino acids. Parts of a protein that are found conserved in many other proteins are called domains; these domains are usually responsible for the protein-protein interactions. Protein-protein interactions (PPIs) are transient or permanent connections between proteins, and they are important for many biological phenomena such as s...

Protein-protein interactions (PPI) play a key role in determining the outcome of most cellular processes. Correctly identifying and characterizing protein interactions and the networks they comprise is critical for understanding the molecular mechanisms within the cell. Large-scale biological experimental methods can directly and systematically detect the set of interacting proteins within an o...

The antimicrobial secondary metabolite kalimantacin (also called batumin) is produced by a hybrid polyketide/non-ribosomal peptide system in Pseudomonas fluorescens BCCM_ID9359. In this study, the kalimantacin biosynthesis gene cluster is analyzed by yeast two-hybrid analysis, creating a protein-protein interaction map of the entire assembly line. In total, 28 potential interactions were identi...