background: quaternary ammonium compounds (qac), which contain benzalkonium chloride as the most widely used agent, are employed as wound and skin antiseptics, as well as disinfectants in hospitals. the resistance mechanism to disinfectants is usually determine by genes which are related to resistance to quaternary ammonium compounds, namely, qace, qacδe1, qacδe1 that are found in gram-negative...

background and objectives: pseudomonas aeruginosa is a frequent opportunistic pathogen in health care associated infections that is highly resistant to the majority of β-lactams. the aims of this study were to access the antimicrobial susceptibility pattern of p. aeruginosa isolated from educational hospitals of qazvin and alborz provinces, to determine the prevalence of metallo-β-lactamase (mb...

background pseudomonas aeruginosa is one of the most important agents causing nosocomial infections worldwide. multidrug resistance of isolated bacteria from nosocomial infections makes it difficult and sometimes impossible to treat. objectives the aim of the present study was to investigate the antibiotic resistance and association between blaimp and blavim genes with resistance to meropenem a...

background carbapenemes are a good choice for treatment of infections caused by multidrug resistant pseudomonads aeruginosa. the emergence of carbapenem resistance has become a major problem in treatment of this organism especially among immunocompromised patients including burn patients. objectives the aim of this study was to investigate carbapenem-resistance mechanisms among burn patients in...

background the effect of pyocyanine pigment, which was isolated and purified from pseudomonas aeruginosa, on specific lymphocytes viability inside the body of white male balb/c mice against the experimental secondary hydatidosis and the infectivity of protoscolices was studied in comparison with negative control mice groups, phosphate buffered saline (pbs) and positive control group (immunofero...

background: in order to select a better antibiotic choice for treatment of pseudomonas aeruginosa infections, this study was conducted to determine the frequency of resistance to some antipseudomonal β-lactams in p. aeruginosa isolates from patients in tehran, iran. in addition, the relation between presence of genes known to be responsible for resistance to β-lactams (ampc, mexc1,2,and mexc3,4...

conclusions the r-b-flagellin carried antigenic epitopes just like the native flagellin, while the polyclonal antibody raised against it exhibited functional activity. results the polyclonal antibodies raised against this r-b-flagellin inhibited the motility of the homologous pao1 strain of p. aeruginosa, which significantly decreased the invasion of the pao1 strain into the a549 cells and also...

background: resistant strains of pseudomonas aeruginosa to imipenem was medical treatment problem, especiallyin burnt units of hospitals. objectives: this study was conducted to evaluate the antimicrobial effect of fe2o3 nanoparticles alone and functionalized with imipenem on p. aeruginosa starins producing metallo b-lactamases (mbl).materials and methods: a disk diffusion method was used to is...

objective: punica granatum, commonly known as pomegranate, has emerged as a medicinal plant with potential antimicrobial activity. the present study was planned to evaluate this activity against both gram positive staphylococcus aureus (s. aureus) and negative pseudomonas aeruginosa (p. aeruginosa) bacteria as well as against pathogenic yeast, candida albicans (c. albicans). material and method...

the objective of this study was to determine the phenotypic characteristics of kpc-producing pseudomonas aeruginosa and acinetobacter baumannii isolates. a case report study was performed at a tertiary burn care centre in tehran,  iran.  nine  isolates  of pseudomonas  aeruginosa  and  acinetobacter baumannii from a hospitalized case were isolated. the identity of isolates was confirmed and the...