The size of repair patch made by E. coli DNA polymerase I (Poll) following the removal of a thymine-psoralen monoadduct by E. coli (A)BC excinuclease was determined by using an M13mp19 DNA with a single psoralen monoadduct at the polylinker region. Incubation of this substrate with (A)BC excinuclease, Poll and a combination of 3 dnTP plus 1 dNTP(alpha S) for each nucleotide, and DNA ligase resu...

We report a case of hybrid thoracic endovascular aortic repair for intercostal patch aneurysm after thoracoabdominal aortic replacement. Eighteen years ago, a 63-year-old woman with Marfan syndrome had undergone thoracoabdominal aortic replacement with reimplantation of the intercostal artery in an island fashion. Follow-up computed tomography (CT) revealed a remaining intercostal patch aneurys...

All across the world, glaucomatologists are adopting broader use of glaucoma drainage implants even as a primary surgical modality. To avoid tube exposure, which may predispose the eye to endophthalmitis, the implanted tube must be covered by a patch graft. However, these patch grafts also carry a high rate of progressive thinning and erosion, which is believed to result from the lack of cellul...

Automated program repair is a problem of finding a transformation (called a patch) of a given incorrect program that eliminates the observable failures. It has important applications such as providing debugging aids, automatically grading assignments and patching security vulnerabilities. A common challenge faced by all existing repair techniques is scalability to large patch spaces, since ther...

The fatigue crack growth behavior of a cracked and patch-repaired AA2024-T3 panel has been monitored by acoustic emission (AE). It was found that the overall crack growth rate was reduced and the crack propagation into the adjacent rivet hole was also retarded by introducing the patch repair. AE signals due to crack growth after the patch repair and those due to disbonding of the aluminum-patch...

The observation that polA1 and recL152 mutations result in both slow pyrimidine dimer excision and large repair patch size leads to the hypothesis that patch size is directly related to the rate of excision. In this study caffeine, a known inhibitor of excision repair, was used to examine the extent of correlation between excision rate and patch size by measuring patch size in the presence of s...

The purpose of this study is to investigate bending moment and the axial load capacity of a pressurized pipe suffering from a through-wall circumferential crack repaired by a composite sleeve. The three-dimensional finite element method (FEM) was adopted to compute the results, and the failure assessment diagram (FAD) was employed to investigate the failure behavior of the repaired pipe. The fi...

BACKGROUND Coronary perforation is a life-threatening complication of percutaneous interventions. In the past few years, the implantation of covered stents has emerged as a strategy for treatment when the traditional conservative approach (ie, prolonged balloon inflation and reversal of anticoagulation) fails. METHODS AND RESULTS Since May 1997 (when polytetrafluoroethylene [PTFE]-covered ste...

Repair of aeronautical structures by composite patch bonding has shown its effectiveness in several studies during the last few decades. This repair technique leads to a retardation propagation repaired cracks via load bridging across throughout adhesive layer, interfacing it with structure. The purpose this study is analyze behavior patch-repaired present thin plates made aluminum alloy 7075-T...