puerperal mortality was higher than in any year . since 1905, and the increase was preponderantly due to sepsis. Last year (1921) the maternal mortality rate fell, but is still far higher than it should be, considering our modern knowledge of the cause and prevention of infection and the successful application of this knowledge to the practice of surgery. In order to arrest this regrettable and...

DURING the last few years attention has been focussed largely on streptococcal infections in the puerperium. I wish to discuss infections with coliform organisms, with special reference to the urinary tract, for although much less serious they are very common and contribute largely to puerperal morbidity. I use the term " pyuria " to mean the presence of both pus cells and organisms in the urin...

We describe a patient readmitted after developing a persistent postural headache resulting from an accidental lumbar puncture during labor 10 days earlier. Magnetic resonance imaging demonstrated bifrontal subdural hygromas and diffuse pachymeningeal enhancement. The patient had signs of a puerperal infection, and an epidural patch was performed with dextran 40 instead of blood, after which gra...

Puerperal sepsis has been known for a long time to be one of the chief causes of the continuously high maternal mortality in this and other countries. In spite of the great advances in antiseptic and aseptic midwifery, and in spite of the fact that we have a much better conception of the nature of infection and of pathogenic organisms, the returns of the Registrar-General in England go to show ...

OBJECTIVE A sample of patients with a puerperal psychosis of an early manifestation is investigated in respect of special risks of suicide and infanticide. METHODS During a 20-year period 96 patients who had been fallen ill with a puerperal psychosis within four weeks after delivery were admitted to a psychiatric university hospital. Patients with an acute exacerbation of a known schizophreni...

OBJECTIVE To determine if amnioinfusion with an antibiotic solution decreased the rate of clinical chorioamnionitis and puerperal endometritis in patients with meconium-stained amniotic fluid. METHODS Patients in labor at 36 weeks of gestation or greater with singleton pregnancies and meconium-stained amniotic fluid were randomized to receive either cefazolin, 1 g/1,000 mL, of normal saline (...

Postpartum women are at increased risk of developing puerperal sepsis caused by group A Streptococcus (GAS). Specific GAS serotypes, including M1 and M28, are more commonly associated with puerperal sepsis. However, the mechanisms of GAS genital tract infection are not well understood. We utilized a murine genital tract carriage model to demonstrate that M1 and M28 GAS colonization triggers TNF...