background thrombolytic therapy in patients with sub-massive pulmonary embolism (smpte) needs further assessment. objectives the current study aimed to assess a potential benefit of thrombolytic and non-thrombolytic therapy in patients with smpte. patients and methods one hundred-nineteen patients were enrolled with smpte from 2006 to 2010 in the tertiary care center of rajaie medical and resea...

The purpose of this study was to assess the effects of acute alterations of the pulmonary circulation on the pulmonic valve echocardiogram. We measured the pulmonic valve opening velocity (PVOV) and right-sided systolic time intervals (right ventricular preejection period-to-right ventricular ejection time ratio [RPEP/RVET] in 22 open-chest dogs subjected to acute hemodynamic alterations produc...

Coronary Artery To the Editor: The echocardiographic images of the anomalous origin of the left coronary artery from the main pulmonary artery presented by Lin et al1 are very instructive. But I disagree with the statement the authors made in the legend of their Figure 3 that “Turbulent flow from the main pulmonary artery through the orifice to the left coronary artery is evident.” In anomalous...

BACKGROUND Pulmonary hypertension is a disease characterized by an elevation in pulmonary arterial pressure that is diagnosed invasively via right heart catheterization. Such pathological altered pressures in the pulmonary vascular system should lead to changes in blood flow patterns in the main pulmonary artery. METHODS AND RESULTS Forty-eight subjects (22 with manifest pulmonary hypertensio...

The surgical treatment of certain congenital anomalies of the right side of the heart characterized by malor non-function of the right auricle or right ventricle or both may depend on the possibility of the direct delivery of blood from the vena cava into the pulmonary arterial circulation.t The immediate and ultimate success of this procedure would depend on the volume of blood flow through th...

OBJECTIVE To assess whether changes in Doppler echocardiographic indices in the pulmonary artery correlated with changes in pulmonary vascular resistance. DESIGN Acceleration time, ejection time, maximal flow velocity, and velocity time integrals were measured at the same time as pressure and oxygen saturation measurements in room air and during 10 minutes of oxygen breathing in the catheteri...

precapillary pulmonary resistance. Pulmonary hypertension is deemed present when the mean pulmonary artery pressure exceeds 25 mm Hg at rest, or 30 mm Hg with exercise. The presence of pulmonary arterial hypertension further requires normal left heart filling pressures (i.e. a normal left ventricular end diastolic pressure directly measured, or indirectly approximated by a pulmonary artery occl...

OBJECTIVE Pulmonary artery occlusion pressure and central venous pressure have been considered to be reliable measures of left and right ventricular preload in patients requiring invasive hemodynamic monitoring. Studies in recent years have questioned the correlation between these estimates of ventricular filling pressures and ventricular end-diastolic volumes/cardiac performance variables in s...

In order to delineate further the function of the main pulmonary artery as a receptor site, a specially designed Laks triple-lumen balloon catheter was inserted transvenously and positioned in the main pulmonary artery. In six conscious nonsedated dogs, inflation of a balloon in the main pulmonary artery produced acute reversible pulmonary arterial hypertension; the pressure beyond the balloon ...