introduction: hypertrophied tonsils and adenoids may cause upper airway obstruction and cardio-pulmonary complications due to pulmonary arterial hypertension. the aim of this study was to determine the correlation between mean pulmonary arterial pressure (mpap) and selected adenotonsilar hypertrophy indexes. materials and methods: thirty two patients with upper-airway obstruction resulting from...

Acute pulmonary hypertension (PH) may arise with or without an increase in vascular smooth muscle (VSM) tone. Our objective was to determine how VSM activation affects both the conduit (CF) and wall buffering (BF) functions of the pulmonary artery (PA) during acute PH states. PA instantaneous flow, pressure, and diameter of six sheep were recorded during normal pressure (CTL) and different stat...

BACKGROUND Several multifactorial risk indexes have been proposed by Western countries for identifying patients at a high risk of developing postoperative pulmonary complications (PPC). However, there is no consensus on how to evaluate the risk of PPC and what multifactorial risk index should be adapted for Japanese patients. This study aimed at clarifying the utility of risk indexes to predict...

STUDY OBJECTIVE The inotropic, lusitropic, and electrophysiologic effects of acute hypercapnia in humans are not known. Although the effects of hypercapnia on the systemic circulation have been well documented, there is still some debate as to whether hypercapnia causes true pulmonary vasoconstriction in vivo. We have therefore evaluated the effects of acute hypercapnia on these cardiac indices...

Introduction: Amyotrophic lateral sclerosis (ALS) is a neurogenic progressive disease that leads to muscle atrophy. The purpose of this study was to evaluate pulmonary function test (PFT) in patients with ALS and its correlation with ASL symptoms. Materials and Methods: This cross-sectional study was performed on 32 ALS patients at Ghaem Hospital, Mashhad...

Benda and Poirot,1 in 1945, in order to avoid the secondary reactions provoked by intravenous injections of procaine, which was recommended for the treatment of dyspnoea by Dos Ghali, Bourdin and Guiot,2 proposed using p-aminobenzoic acid (PAB) in the place of procaine. It is known that the latter, once in contact with the blood plasma transforms itself rapidly into p-aminobenzoic acid and diet...

Introduction: Renal failure affects the mechanical and the ventilatory function of the lungs. A few studies have evaluated the ventilatory and pulmonary function in dialysis patients. The present study aimed to compare Pulmonary Function Test (PFT) results in patients undergoing Hemodialysis (HD) and Peritoneal Dialysis (PD). Materials and Methods: We conducted a cross-sectional study on 50  pa...

Background The outcome of the Fontan operation largely depends on patient selection because this procedure is a physiological correction. Among the several selection criteria for the Fontan operation, the importance of adequate size of the pulmonary artery remains controversial. To clarify whether or not pulmonary artery size is indispensable as one of the selection criteria for the Fontan oper...

introduction chronic obstructive pulmonary disease (copd) is a chronic disorder with many systematic complications and one of the most important reasons for patients to require mechanical ventilation, admission in intensive care unit and prolonged mechanical ventilation. although the first attempt in separation of mechanical ventilation is failed in half of chronic obstructive pulmonary disease...

BACKGROUND Ventricular function has conventionally been characterized using indexes of systolic (contractile) or diastolic (relaxation/stiffness) function. Systolic indexes include maximum elastance or equivalently the end-systolic pressure volume relation and left ventricular ejection fraction. Diastolic indexes include the time constant of isovolumic relaxation - and the end-diastolic pressur...