Aim. This study investigated the effect of P6 EA on droperidol-induced QTc interval prolongation and Cx43 expression in ventricular muscle of rats. Methods. Twenty-four rats were randomly divided into control group (C), droperidol group (D), or EA group (E). C group rats were injected with normal saline. D group rats were injected with droperidol 0.13 mg/kg. E group rats were pretreated with EA...

BACKGROUND AND OBJECTIVES Excessive catecholamine causes the alteration of cardiac structure and function. This study evaluated if there is any difference in left ventricular hypertrophy (LVH) and QTc prolongation in conditions with pheochromocytoma and Takotsubo cardiomyopathy (TC). SUBJECTS AND METHODS We reviewed the medical records of 20 pheochromocytoma patients for cardiovascular events...

BACKGROUND In myocardial infarction patients, heart rate-adjusted QT interval (QTc), an electrocardiographic indicator of sympathetic balance, is prognostic for survival. METHODS AND RESULTS In a 28-year follow-up, the association between QTc and all-cause, cardiovascular, and ischemic heart disease mortality was studied in a population of 3,091 apparently healthy Dutch civil servants and the...

Background: The goal was to use surface electrocardiographic (ECG) indicators detect COVID-19's malignant arrhythmic potential.
 Methodology: In 51 COVID-19 patients and 40 control subjects, the ECG parameters PR, QT, QTc, QTd, TPe, Tpe/QTc were assessed. had substantially higher mean QTc (410.8 24.3 msec vs. 394.6 20.3 msec, p.001), (0.19 0.02 0.18 0.04, p =.036), median QTd (47.52 46.5) ...

BACKGROUND Chronic arsenic exposure is associated with cardiovascular abnormalities. Prolongation of the QT (time between initial deflection of QRS complex to the end of T wave) interval and profound repolarization changes on electrocardiogram (ECG) have been reported in patients with acute promyelocytic leukemia treated with arsenic trioxide. This acquired form of long QT syndrome can result i...

BACKGROUND This study evaluated the effects of atypical antipsychotic drugs and selective serotonin reuptake inhibitors (SSRIs) on the corrected QT (QTc) interval using a large database obtained from clinical settings. Additionally, the effects of factors including age on QTc intervals were estimated. METHODS Using an open-access QT database (ECG-ViEW), QTc-lengthening effects of 14 selected ...