Background & Objective: Malignant melanoma is the fatal cutaneous neoplasm which is curable by the early diagnosis. The expression of occludin protein which is an integral membrane protein is altered in an epithelial-to-mesenchymal transition. Although, recent studies provide sufficient evidence supporting the functional importance of occludin in cancer, the prognostic signific...

purpose: to evaluate the health-related quality of life (hrqol) among strabismus patient. methods: one hundred and twenty-two strabismic patients ≥ 14 years who scheduled for surgery were selected non-randomly. the patients completed the adult strabismus 20 (as-20) and sf 36 questionnaires. measurements were performed preoperatively and 3 and 6 months postoperatively. changes in psychosocial an...

conclusions based on the results of the present study and other performed studies in this regard, menopause, aging, vasomotor symptoms, and education had significant association with the qol of postmenopausal women. the reduced qol in postmenopausal women could eventually lead to the reduced qol of their spouses. therefore, it is necessary to plan for the education of these women and their husb...

The Siberian sturgeon (Acipenser baerii) is an economically important species. Sturgeon stockassessment during fingerling production is considered to be one of the most difficult phases ofhatchery rearing. The present study investigated the expression of growth hormone (GH)mRNA in unfertilized eggs, fertilized eggs, eyed eggs (2 day before hatching), non-viable eggsand newly-hatched Siberian st...

Background and Objectives: Cyclooxygenese-2 (COX-2) expression in breast cancer and its correlation with tumor prognosis is unclear. We investigated the incidence of COX-2 expression in patients and assessed interactions between COX-2 and clinical features of cancer and expression of HER2/neu, estrogen receptor (ER), and progesterone receptor (PR). Methods: COX-2 expression was investigated by...

Background and Aims: Smoking has an influence on different semen parameters. It is regarded as a risk factor for infertility. This study aims to evaluate the effect of smoking cigarettes on the expression of nuclear factor erythroid 2-related factor 2 (NRF2) and glutathione S-transferase Mu 1 (GSTM1) genes and biomarkers of oxidative stress in sperm. Materials and Methods: A case-control study...

Background: Polycystic ovary syndrome (PCOS) is a disorder of hyperandrogenemia and chronic anovulation which affects 5-10% of all women. The PCOS symptoms such as hirsutism, irregular menses, obesity and infertility are a major source of psychological morbidity and can negatively affect quality of life. In this study, we examined the health-related quality of life among Iranian women who suffe...