نتایج جستجو برای: quinine
تعداد نتایج: 2987 فیلتر نتایج به سال:
BACKGROUND Severe malaria is a major cause of childhood death and often the main reason for paediatric hospital admission in sub-Saharan Africa. Quinine is still the established treatment of choice, although evidence from Asia suggests that artesunate is associated with a lower mortality. We compared parenteral treatment with either artesunate or quinine in African children with severe malaria....
In a case of quinine-induced agranulocytosis marrow culture studies confirmed the inhibitory effect on the patient's cells of equivalent therapeutic plasma concentrations of quinine. Similar concentrations had no effect on normal marrow cells. Quinidine, the stereoisomer of quinine, had no effect on either cells from the patient or normal cells. The results encourage the use of in-vitro bone ma...
Quinoidine was greater than that of Quinine and this honour has often been awarded to it since, though very little of the drug appears to have been used except as a tonic for horses. Major Waters' recent paper in the IMG seems to be having a greater effect on its sale. In every Quinine factory Quinine alone has been the important product. The other alkaloids are listed and occasionally one or o...
BACKGROUND Because antimalarial drug resistance is spreading, there is an urgent need for new combination treatments for malaria, which kills >1 million people every year. Azithromycin is a macrolide antibiotic that is particularly attractive as an antimalarial because of its safety in children and the extensive experience with its use during pregnancy. METHODS We undertook a randomized, cont...
• Quinine binds to quininedependent antibodies first and causes CDR loop reconfiguration. • A hybrid paratope consisting of quinine and reconfigured CDR recognizes its target epitope. Drug-induced immune thrombocytopenia (DITP) is caused by antibodies that react with specific platelet-membrane glycoproteinswhen the provokingdrug is present.More than 100 drugs have been implicated as triggers fo...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید