Vigna vexillata (L.) A. Rich. (tuber cowpea) is an underutilized crop for consuming its tuber and mature seeds. Wild form of V. vexillata is a pan-tropical perennial herbaceous plant which has been used by local people as a food. Wild V. vexillata has also been considered as useful gene(s) source for V. unguiculata (cowpea), since it was reported to have various resistance gene(s) for insects a...

With the impetus of quantized derivations, renewed interest in the general Ore extension T = R[t;S,D] has arisen during the last few years. The prime radical of T is currently being analyzed (e.g. [G]) and in the special cases when either S = id or D = 0 it has been completely described ([FKM], [PS]). In the former case this description is very much like that for the ordinary polynomial ring, i...

Fol lowing the enormous increase in the use of wireless mobile telephony across the wor ld concerns on hea l th e f fec t s o f hand-he ld mobi le phone rad ia t ions have induced a l a rge body of research , bo th ep idemio log ica l and exper imenta l . Th is wi re less t echnology uses e lec t romagne t ic radiation in microwave range which may be harmful to human health. Parts of the radio ...

The interplay between free charge carriers, transfer (CT) states and singlet excitons (S1) determines the recombination pathway resulting open circuit voltage (VOC) of organic solar cells. By combining a well-aggregated low bandgap polymer with different blend ratios fullerenes PCBM ICBA, energy CT state (ECT) is varied by 130 meV while leaving S1 ( E S 1 \[{E_{{{\rm{S}}_1}}}\] ) unaffected. It...

BACKGROUND Rad (Ras associated with diabetes) GTPase is the prototypic member of a subfamily of Ras-related small G proteins. The aim of the present study was to define whether Rad plays an important role in mediating cardiac hypertrophy. METHODS AND RESULTS We document for the first time that levels of Rad mRNA and protein were decreased significantly in human failing hearts (n=10) compared ...

BACKGROUND AND OBJECTIVES Modern imaging techniques have increased the incidental detection of renal atherosclerotic disease (RAD). Because immune activation may hasten RAD progression, identifying cellular immune markers might provide clues to clinical activity. In this study, cellular immune markers were assessed in early RAD. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS Immune cell marker...

The new immunosuppressive agent, SDZ-RAD, and its analog rapamycin were examined for intestinal absorption, metabolism, and bioavailability in Wistar rats. Intestinal first-pass metabolism studies from rat jejunum showed that at 0.5 mg of SDZ-RAD/kg rat, 50% of the parent compound was metabolized in the intestinal mucosa, and this decreased to around 30% when SDZ-RAD was increased to 5.0 mg/kg ...

BACKGROUND The small GTPase Rad is a negative regulator of voltage-dependent L-type calcium channel current (ICaL); however, the effects of Rad ablation on cardiomyocyte function are unknown. The objective of this study is to test the hypothesis that Rad-depletion causes positive inotropic effects without inducing cardiac hypertrophy. METHODS AND RESULTS Ventricular myocytes from adult Rad(-/...

A recombinant adenovirus (rAd) expressing Cre recombinase derived from bacteriophage P1 has already been extensively used for the conditional gene activation and inactivation strategies in mammalian systems. In this study, we generated AxCAFLP, a rAd expressing FLP recombinase derived from Saccharomyces cerevisiae and carried out quantitative comparisons with Cre-expressing rAd in both in vitro...

Disorders of L-type Ca channels can cause severe cardiac arrhythmias. A subclass of small GTP-binding proteins, the RGK family, regulates L-type Ca current (ICa,L) in heterologous expression systems. Among these proteins, Rad (Ras associated with diabetes) is highly expressed in the heart, although its role in the heart remains unknown. Here we show that overexpression of dominant negative muta...