Radiographic contrast media: A new risk for pulmonary aspiration ? Joseph Eldor (1), Vladimir Kotlovker (2), Virgil Priscu (3) Department of Anesthesia, Kaplan Medical Center, Hebrew University and Hadassah, Rehovot, Israel (1)(2) Senior staff Anesthesiologist (3) Head of Department Aspiration of high osmolar water soluble radiographic contrast media (RCM) is dangerous and can induce sever...

BACKGROUND Intra-arterial administration of radiographic contrast media (CM) is discussed to impair renal perfusion. The pathogenesis of contrast-induced Nephropathy (CIN) is still not clarified. OBJECTIVE This trial was performed to prove the effects of two CM with different molecular structure on renal perfusion. METHODS A prospective, randomized study on 16 pigs was designed to compare t...

The effect of the radiographic contrast agents, iopamidol and diatrizoate, on fibrin assembly and structure as well as platelet surface charge was studied. Increasing the iopamidol concentration from 0 to 4.5 mM prolongs the fibrin gelation time from 20 to 105 seconds (an anticoagulant effect) and reduces the fibrin fiber mass/length ratio from 3.2 x 10(12) to 0.5 x 10(12) Da/cm (i.e., produces...

It is well known that iodinated radiographic contrast media may cause kidney dysfunction, particularly in patients with preexisting renal impairment associated with diabetes. This dysfunction, when severe, will cause acute renal failure (ARF). We may define contrast-induced Acute Kidney Injury (AKI) as ARF occurring within 24-72 hrs after the intravascular injection of iodinated radiographic co...

Differential phase-contrast imaging with hard x rays can have important applications in medicine, material sciences, and energy research. Phase-contrast methods based on microperiodic optics, such as shearing interferometry, are particularly attractive because they allow the use of conventional x-ray tubes. To enable shearing interferometry with x rays up to 100?keV, we propose using grazing-in...

Gold nanoparticles (GNPs) are being proposed as contrast agents to enhance X-ray imaging and radiotherapy, seeking to take advantage of the increased X-ray absorption of gold compared to soft tissue. However, there is a great discrepancy between physically predicted increases in X-ray energy deposition and experimentally observed increases in cell killing. In this work, we present the first cal...

BACKGROUND AND OBJECTIVES Measurement of GFR is important for the management of chronic kidney disease (CKD). Although bolus administration of radiocontrast agents is commonly used to measure GFR, the optimal duration of sampling to assess their plasma clearance is unknown. The purpose of this study was to evaluate whether the duration of plasma sampling influences precision and estimation of G...

Magnetic particles are broadly used for separating different components of a sample. The visualization of magnetic particles is very essential for qualitation and quantification of the components. However, conventional x-ray imaging techniques still have difficulties to clearly show magnetic particles especially when their x-ray attenuation is weak. Synchrotron radiation (SR) phase contrast ima...

Advances in microscopy techniques based on x-rays have opened unprecedented opportunities in terms of spatial resolution, combined with chemical and morphology sensitivity, to analyze solid, soft and liquid matter. The advent of ultrabright third and fourth generation photon sources and the continuous development of x-ray optics and detectors has pushed the limits of imaging and spectroscopic a...