Assessing response to therapy allows for prospective end point evaluation in clinical trials and serves as a guide to clinicians for making decisions. Recent prospective and randomized trials suggest the development of imaging techniques and introduction of new anti-cancer drugs. However, the revision of methods, or proposal of new methods to evaluate chemotherapeutic response, is not enough. T...

objectives to compare an out-of-plane interscalene catheter technique to the in-plane technique in a randomized clinical trial. patients and methods eighty-four patients undergoing open shoulder surgery were randomized to either the in-plane or out-of-plane ultrasound-guided continuous interscalene technique. the primary outcome was vas pain rating at 24 hours. secondary outcomes included pain ...

In this paper, we propose a new quantitative randomized response model based on Mangat and Singh [7] two-stage randomized response model. We derive the estimator of the sensitive variable mean, and show that our method is more efficient than other randomized response models suggested by Greenberg et al. [3] and Gupta et al. [4] estimators.

Response distortion attributable to a variety of human motivations has long been a recognized problem for behavioral research relying on self reports by individuals. Researchers studying unethical IS behaviors usually need to solicit self reports because of the secrecy of such behaviors. Unfortunately, the unethical nature of those behaviors often subject self reports to various response distor...

Background The purpose of this prospective randomized study was to compare ovarian response as well as oocytes embryo yields and pregnancy rates in women who underwent ovulation induction for intracytoplasmic sperm injection (ICSI) with recombinant human FSH (rFSH) alone or in combination with human menopausal gonadotropin (HMG). MaterialsAndMethods Out of 300 patients in assisted reproductive ...