Rap1, is required to define the position of the new bud. 1997). In vitro, this interaction is not sufficient to stimulate the GEF activity of Cdc24p, and one functional out-and Molecular Biology University College London come of this interaction in vivo, therefore, is likely to be the localization of Cdc24p to the presumptive bud site London WC1E 6BT United Kingdom (Zheng et al., 1995). In S. p...

Cell transformation is clearly linked to epigenetic changes. However, the role of the histone modifying enzymes in this process is still poorly understood. In this study we investigated the contribution of the Histone Acetyltransferase (HAT) enzymes to Ras mediated transformation. Our results demonstrated that lysine acetyltransferase 5 (KAT5), also known as Tip60, facilitates histone acetylati...

El Departamento de Ingeniería Química la Universidad Concepción ha presentado su carrera Civil al proceso acreditación ante agencia norteamericana ABET. eje se centra en un mejoramiento continuo que requiere ajustar el enseñanza a nuevas formas medición, control y evaluación. Se presenta modelo implica cambios cultura medición evaluación las asignaturas, hacia uno centrado logro resultados apre...

The house fly, Musca domestica L., is a very important insect because of its role as a vector of several human, livestock, and poultry diseases. Different groups of insecticides, including the pyrethroids, are used to control house flies. The objective of the current study was to conduct a survey of the kdr insecticide resistance gene in the house fly population in the United Arab Emirates (UAE...

Our knowledge of understanding the complex role of renin angiotensin system (RAS) or RA system in human physiology has been widened for more than 100 years and it is rapidly increasing day-by-day. Over the last two decades discoveries of angiotensin converting enzyme 2 (ACE 2), putative receptor for angiotensin (Allen et al., 2006; Aronsson et al. 1988; Bickerton & Buckley, 1961; Cooper et al.,...

The Reproducibility Project: Cancer Biology seeks to address growing concerns about reproducibility in scientific research by conducting replications of selected experiments from a number of high-profile papers in the field of cancer biology. The papers, which were published between 2010 and 2012, were selected on the basis of citations and Altmetric scores (Errington et al., 2014). This Regist...

colorectal cancer (crc) is one of the most common cancers worldwide. understanding of the tumor behavior, in a much closer look, at the molecular level, results in a more effective treatment and accurate prognosis of the disease. from among various genes altered in colorectal cancer k-ras is assumed to be of diagnostic and prognostic significance. k-ras mutations are believed to be a critical e...

Background: Recurrent aphthous stomatitis (RAS) is the most common inflammatory ulcerative condition of oral cavity. The aim of this study was to compare the levels of the salivary Malondialdehyde (MDA) and total antioxidant capacity (TAC) and blood parameter in RAS versus healthy controls. Methods: This case-control study consisted of 28 patients with RAS and 28 age and sex -matched control...

The Reproducibility Project: Cancer Biology seeks to address growing concerns about reproducibility in scientific research by conducting replications of selected experiments from a number of high-profile papers in the field of cancer biology. The papers, which were published between 2010 and 2012, were selected on the basis of citations and Altmetric scores (Errington et al., 2014). This Regist...

Background: Recurrent aphthous stomatitis (RAS) is a common disease, which several etiologic factors have been considered for it. The infectious agents and immunological factors are the most suspected causes. Recently a few studies with varied results have been done to clarify the role of Helicobacter Pylori (H.pylori) in etiology of RAS. Objective: To find correlations between serum IgG and Ig...