The potential advantages of 0.25% concentration of levobupivacaine in performing lumbar plexus with sciatic and iliohypogastric nerve block in patients with aortic stenosis is emphasized in this case report. A 48-yr old male patient who was scheduled for hip fracture surgery had severe aortic stenosis with aortic valve gradient of 85 mmHg. Anesthesia plan was combined lumbar plexus, sciatic and...

Dexamethasone is currently used for the treatment of peripheral nerve injury, but its mechanisms of action are not completely understood. Inflammation/immune response at the site of nerve lesion is known to be an essential trigger of the pathological changes that have a critical impact on nerve repair and regeneration. In this study, we observed the effects of various doses of dexamethasone on ...

BACKGROUND The use of peripheral nerve blocks in patients with Charcot-Marie-Tooth (CMT) disease is scarcely reported; however, when performed it has proven to be effective for postoperative pain control. METHODS A distal catheter-based sciatic nerve block for postoperative pain control was offered to 27 consecutive CMT patients scheduled for elective foot surgery. 18 of the 27 CMT patients c...

UNLABELLED BACKGROUND The widespread of hallux valgus surgery in a day care setting enhanced the role of regional anaesthesia in the last few years. Sciatic nerve block at popliteal fossa has been shown to provide safe and effective analgesia. Our purpose was to compare the success rate and performance time of popliteal block during resident's training for regional anaesthesia by using nerve...

We investigated the identities of the isoforms of the α (NaV1)- and β (NaVβ)-subunits of voltage-gated sodium channels, including those responsible for action potentials in rodent sciatic nerves. To examine α-subunits, we used seven μ-conotoxins, which target site 1 of the channel. With the use of exogenously expressed channels, we show that two of the μ-conotoxins, μ-BuIIIB and μ-SxIIIA, are 5...

Objective: Uncontrolled postoperative pain and nausea and vomiting are the most common causes for hospital admission following ambulatory anterior cruciate ligament (ACL) reconstruction. Therefore, finding techniques that provide excellent postoperative pain control is of critical importance. This retrospective study compared patients who received preoperative femoral nerve blockade to those wh...

Histological and electrophysiological studies were performed on Lewis rats with acute experimental allergic encephalomyelitis (EAE) induced by inoculation with guinea-pig myelin basic protein (MBP) and Freund's adjuvant. The histological studies showed demyelination in the lumbar, sacral and coccygeal dorsal and ventral spinal roots and to a lesser extent in the spinal cord, including the dorsa...

There have not been yet enough studies about effects of beta glucan and gliclazide on oxidative stress created by streptozotocin in the brain and sciatic nerve of diabetic rats. The aim of this paper was to investigate the antioxidant effects of gliclazide and beta glucan on oxidative stress and lipid peroxidation created by streptozotosin in brain and sciatic nerve. Total of 42 rats were divid...

BACKGROUND AND OBJECTIVES In 2003 we introduced the concept of a sciatic nerve block performed in the midgluteal area at a fixed distance from the midline in all adults regardless of gender and/or body size. The anatomic basis for that study suggested that a subgluteal block could also be accomplished in a similar fashion. METHODS After informed consent, 20 patients were prospectively recruit...

objective: to assess the effect of combination of pulsed electromagnetic fields (pemf) with predatory stress on transected sciatic nerve regeneration in rats.  methods: in sham- operated group (sog) the nerve was manipulated and left intact. the 10-mm rat sciatic nerve gap was created in rats. in transected group (transected) nerve stumps were sutured to adjacent muscle and in vein graft group ...