This report documents a case of intravascular lymphoma (IVL) with increased regional cerebral blood flow (rCBF) disclosed at I-123 IMP single-photon emission CT (IMP-SPECT). A 73-year-old woman with IVL had high rCBF disclosed by IMP-SPECT before chemotherapy; rCBF was normal after one course of CHOP (cyclophophamide, vincristine, doxorubicin, and prednisone) chemotherapy. During her clinical c...

In order to investigate, during activation testing, the interictal cortical cerebral blood flows (rCBF) of epileptic patients suffering from complex partial seizures, 40 epileptic patients (divided into "lesional", this is, with abnormal CT findings, and "non lesional", that is, with normal CT findings) were submitted to rCBF measurements with the 133 xenon intravenous technique, at rest and du...

AIMS To determine the effect of diabetes mellitus (DM) on regional cerebral blood flow (rCBF) patterns in patients with Alzheimer's disease (AD). METHODS We investigated the initial rCBF of 71 AD patients (36 without DM and 35 with DM) and the final rCBF of 23 AD patients (12 without DM and 11 with DM) after an average of 32 months. Single-photon emission computed tomography (SPECT) data were...

Cerebral Blood Flow Measurement as a Safeguard During Carotid Endarterectomy • Intraoperative measurement of regional cerebral blood flow (rCBF) by the Xe intracarotid injection technique was performed in 17 patients operated on for stenosis of the internal carotid artery. Mean rCBF decreased from 51 ml/100 gm x minute before endarterectomy to 30 ml/100 gm x minute when the internal carotid art...

BACKGROUND AND PURPOSE We previously reported that L-arginine infusion increased pial vessel diameter by nitric oxide-dependent mechanisms, improved regional cerebral blood flow (rCBF) distal to middle cerebral artery (MCA) occlusion, and reduced infarction volume in spontaneously hypertensive rats when administered intraperitoneally before and after MCA occlusion. In this report we extend our ...

BACKGROUND The precise neural mechanisms of propofol anesthesia in humans are still unknown. The authors examined the acute effects of propofol on regional cerebral blood flow (rCBF) using positron emission tomography in patients with severe depression. METHODS In six severely depressed patients (mean age, 55.0 yr) scheduled for electroconvulsive therapy, anesthetic levels were monitored by e...

The objective of this investigation was to correlate Xenon-133 inhalation rCBF measurements with the pattern of cortical arterial filling on intravenous DSA in 18 patients with unilateral internal carotid artery occlusion. Of 9 patients showing symmetrical filling of hemispheric cortical arteries, none showed an inter-hemispheric difference in rCBF ( delta Fg) greater than 10ml/100gm/min. Of 9 ...

BACKGROUND Although depression is highly prevalent in Parkinson disease (PD), little is known about the neural correlates associated with depression and antidepressant treatment in PD. OBJECTIVE To examine the effects of fluoxetine and repetitive transcranial magnetic stimulation (rTMS) on regional cerebral blood flow (rCBF) using SPECT in patients with PD and depression. METHODS Twenty-six...

PURPOSE To compare an ultrafast CT method for estimating regional cerebral blood flow with a more commonly used xenon-enhanced CT method. METHODS Xenon CT and ultrafast CT were used to estimate regional cerebral blood flow (rCBF) in 12 healthy beagle dogs. Measurements were obtained for left and right hemisphere, cortical gray matter, basal ganglia, and deep white matter. The ability of each ...

Regional cerebral blood flow (rCBF) was measured using H2(15)O and positron emission tomography (PET) to test the hypothesis that age-related changes in the pattern of rCBF activation would be greater under divided attention conditions than under selective attention conditions. Subjects were 24 right-handed men: 12 young adults (age 21-28 years), and 12 older adults (age 60-77 years). Measureme...