In this paper, the major upgrades and technical improvements of buffer gas handling system for cryogenic stopping cell FRS Ion Catcher at GSI/FAIR (in Darmstadt, Germany) are described. The include implementation new lines purifiers to achieve a higher cleanliness more efficient extraction reactive ions as well suppression molecular background ionized in cell. Furthermore, additional techniques...

BACKGROUND Reactive oxygen species have been shown to mediate inflammatory process and may be involved in lipid peroxidation. METHODS This study evaluates superoxide dismutase, glutathione peroxidase, catalase, malondialdehyde, C- reactive protein and fibrinogen in the serum of patients with sickle cell disease and their correlation with renal insufficiency. Superoxide dismutase, glutathione ...

By immunizing mice with killed whole bacterial cells of Brucella abortus S (99), a panel of six hybridomas producing monoclonal antibodies (mAb) specific for the surface antigens of this bacterium were produced. ELISA was used to screen the hybridoma supernatants. Immunoblots of the cell extract indicated that three mAb were specific for S-LPS (Ba-1, Ba-2, Ba-3) and three others were reactive w...

Objective(s):  The role of the Apoptosis repressor with caspase recruitment domain (ARC) in apoptosis and in certain hypertrophic responses has been previously investigated, but its regulation of Endothelin-1 induced cardiac hypertrophy remains unknown. The present study discusses the inhibitory role of ARC against endothelin–induced hypertrophy. Results:In present study Endothelin treated car...

HIGHLIGHTS Ischemia-reperfusion triggers acute kidney injury due to reactive oxygen species. Quercetin is an antioxidant flavonoid that modulate the Rennin-Angiotensin System. prevents tubular cell death, oxidation, and mitochondrial depolarization. interacts with angiotensin AT1 receptor.

reactive oxygen species (ros)plays an important role in sperm motility. the physiological generation at low concentration induces beneficial effects on sperm functions and plays a significant role in sperm metabolism. meanwhile, the excessive generation of reactive oxygen species can overwhelm protective mechanism and triggers changes in lipid and protein layers of sperm plasma membrane, which ...

objective we have previously shown that rose bengal (rb) alone, not as a photosensitiser, could induce apoptotic- and non-apoptotic cell death in different melanoma cell lines. to clarify rb-induced toxicity mechanisms, role of caspases and reactive oxygen specious (ros) were studied in melanoma cells. material and methods human melanoma cell lines, me 4405 and sk-mel-28 were cultured in dmem m...

conclusions in our study, no prominent effect was seen; therefore, in order to have a better perspective of crocin activity against cancerous cell lines, further studies are highly recommended. results the highest concentration of crocin significantly decreased ros production after 48 hours of treatment. however, crocin had no effect on the expression level of hsp (heat shock protein). addition...

Normal and immune sera from various animal species were fractionated on columns of Sepharose covalently coupled with the glycoprotein fetuin. Elution of the material bound to fetuin yielded low but reproducible amounts of protein, ranging from 0.02 to 0.2% of the protein mass of the input sera. This material has been identified by immunoelectrophoresis in agar and by zone electrophoresis on cel...

process of activation, division, and differentiation to generate a large pool of activated effector T cells. Regulated induction of apoptosis of these expanded T cells avoids several problems for the host, including increased metabolic cost, disruption of lymphoid homeostasis, and predisposition to autoimmunity and lymphoid neoplasia. On the other hand, it is essential that some activated T cel...