Dear Editor, Recently, we diagnosed a 50-year-old woman as having reactive lymphoid hyperplasia (RLH) of the uvea, and herein we report that this is the first diagnosis of this condition in a Korean patient. The patient was referred to the ophthalmology clinic with blurry vision due to choroidal mass-like lesions of the right eye for 1 month. Uncorrected visual acuity (UCVA) of the right eye wa...

OBJECTIVE To assess the magnitude and causes of over-diagnosis of prostatic intraepithelial neoplasia (PIN), as large differences are reported in the incidence of high-grade PIN, probably because of the variance in diagnosis and interpretation. PATIENTS AND METHODS Two urological pathologists prospectively reviewed 251 consecutive patients, received in consultation and who were diagnosed and ...

Background: Differentiation of benign from malignant mesothelial proliferations is a major problem in the pathology of the serosal membranes, particularly in small biopsy specimen. This study was conducted for the evaluation of proliferative marker for distinction between malignant mesothelioma (MM) and mesothelial hyperplasia (MH). Materials and Methods: Thirty six cases of malignant mesotheli...

the histopathologic diagnosis of orbital and ocular adnexal lymphoproliferative lesions is difficult, resulting controversy in classification, determining benignity or malignancy of them and treatment modality selection. we designed the following study to evaluate clinical, histopathologic and if necessary immunochemical features of them in decreasing indeterminate cases. the study includes 51 ...

This article reviews mechanisms of chemical carcinogenesis, from metabolic activation and generation of reactive oxygen species by cytochromes P4511 and P4502E to DNA damage, activation of protein kinase C and ocogenes, hyperplasia, and proteoglycan changes in the cell glycocalyx and lysosomal enzymes which mediate invasion and metastasis.

Post-transplant lymphoproliferative disorder is the most common malignancy, with the exception of skin cancer, after solid organ transplantation in adults. The incidence varies according to the transplanted organ and is often associated with Epstein-Barr virus. Prognosis is variable, due in part to the heterogeneity of the disease, which ranges from reactive plasmacytic hyperplasia to aggressiv...

Lung cancer remains one of the most common malignant tumors. Identifying cervical lymph node metastases is important to stage lung cancer, evaluate patients’ prognosis and select appropriate treatments. This study evaluated utility conventional ultrasound combined with contrast-enhanced (CEUS) quantitative analysis in diagnosing nodes neck. The 39 patients primary who underwent CEUS ultrasound-...