PURPOSE Hypofractionated radiotherapy has an intrinsically different normal tissue and tumor radiobiology. The results of a prospective trial of stereotactic body radiotherapy (SBRT) for prostate cancer with long-term patient-reported toxicity and tumor control rates are presented. METHODS AND MATERIALS From 2003 through 2009, 67 patients with clinically localized low-risk prostate cancer wer...

introduction: multiple fields and presence of heterogeneities create complex dose distributions that need three dimensional dosimetry. in this work, we investigated mr-based magic gel dosimetry as a three-dimensional dosimetry technique to measure the delivered dose to bladder and rectum in prostate radiation therapy. materials and methods: a heterogeneous slab phantom including bones was made....

Introduction. A favorable outcome of the treatment patients with rectal cancer in early stages is not a difficult task, as it easily solved thanks to only surgical intervention. The biggest problem late-stage (III and IV) cancer. use radiation therapy an integral niche complex Complete or partial clinical response tumor neoadjuvant factor that correlates increase overall recurrence-free surviva...

The majority of current models utilized for predicting toxicity in prostate cancer radiotherapy are based on dose-volume histograms. One of their main drawbacks is the lack of spatial accuracy, since they consider the organs as a whole volume and thus ignore the heterogeneous intra-organ radio-sensitivity. In this paper, we propose a dose-image-based framework to reveal the relationships betwee...

Background . During the COVID-19 pandemic, annual adult check-ups have been postponed, resulting in cancer screening disruption. The aim of study was to evaluate changes incidence and stage distribution malignancies included program during pandemic using Arkhangelsk Regional Cancer Registry (ARRC). Material Methods We assessed rates for colon, rectum, lung, breast, cervix, uterine body, ovary, ...

The increased frequency of PSA testing has led to an increased diagnosis of early organ confined prostate cancer. Diagnosis is primarily made by histology, via TRUS-guided sextant biopsy or template biopsy which can provide improved localisation of cancer within the prostate. Staging is from digital rectal examination, from imaging with multi-parametric MRI (TNM staging), from PSA levels, and f...

Introduction: The accuracy of the patient setup and tumor location are major factors that determine the efficacy of radiotherapy treatment planning. In the prostate radiotherapy, reproducibility of the prostate location for each treatment fraction is problematic owing to varying filling of the rectum and bladder. According to this, the aim of this study was to measure the inte...

PURPOSE The aim of the study was to analyze early effects and toxicity of salvage high dose rate brachytherapy for local recurrences of adenocarcinoma of the prostate after external beam radiotherapy (EBRT). MATERIAL AND METHODS In MCS Memorial Institute of Oncology in Gliwice a research programme on salvage HDR brachytherapy for local recurrences of prostate cancer treated previously with EB...