BACKGROUND Acute bacterial meningitis which is a pediatric emergency with high mortality and morbidity must be diagnosed and treat promptly. Often diagnosis of bacterial meningitis from viral meningitis is difficult after some days. Determination of some inflammatory mediators' example IL-6 and HS-CRP were useful in differential diagnosis of bacterial and viral meningitis. OBJECTIVES This stu...

OBJECTIVE To review the ages of patients with recurrent herpes simplex virus type 2 (HSV-2) meningitis. DESIGN Case report and literature review back to 1970. SETTING Referral Veterans Affairs hospital. RESULTS Our patient developed his first episode of recurrent HSV-2 meningitis at 78 years of age, 57 years after his only episode of genital herpes simplex infection. Of 223 patients in th...

Mondini dysplasia, also known as Mondini malformation, is a developmental abnormality of the inner and middle ears that can cause hearing loss, cerebrospinal fluid (CSF) leakage, and recurrent bacterial meningitis (RBM), which is defined as two or more episodes of meningitis separated by a period of convalescence and the complete resolution of all signs and symptoms. An accurate diagnosis of th...

Multiple cysts in both hemispheres were detected in four children under 1 year of age by real-time sonographic sector scanning. These cysts, typical of multiple cystic encephalomalacia, followed viral encephalitis in two, bacterial meningitis in one, and bacterial meningitis superimposed on intracerebral hemorrhage in one. The diagnosis of multiple cystic encephalomalacia, which has a grave pro...

OBJECTIVES To determine the level of serum procalcitonin, blood leukocyte count (TLC) and C-reactive protein (CRP) in children with bacterial and non bacterial meningitis and document their efficacy in differential diagnosis. Also described are procalcitonin levels variation during treatment. METHODS From March 2005 to February 2008, we evaluated 38 clinically suspected meningitis patients in...

OBJECTIVES Bacterial meningitis is a severe but treatable condition. Clinical symptoms may be ambiguous and current diagnostics lack sensitivity and specificity, complicating diagnosis. Procalcitonin (PCT) is a protein that is elevated in serum in bacterial infection. We aimed to assess the value of PCT in cerebrospinal fluid (CSF) in the diagnosis of bacterial meningitis. METHODS We included...

Introduction: The early presentation of bacterial meningitis and aseptic are similar however treatment outcome different. Bacterial Meningitis Score helps to differentiate from meningitis.
 Aims: To evaluate score as clinical prediction rule in children with acute Methods: This was a hospital based prospective study done at pediatric department Nepalgunj Medical College, Nepalgunj, tertiar...

INTRODUCTION Cases of idiopathic recurrent benign aseptic meningitis were first described by Mollaret. Today, herpes simplex virus (HSV) is considered the cause of most cases of Mollaret's meningitis. CASE REPORT A 40-year-old male was referred to our genitourinary medicine clinic with recurrent genital herpetic lesions. He had HSV-2-positive genital ulcers 8 years earlier. One year after the...