Distal protection devices such as FilterWire EX have been widely used in carotid artery stenting, however, the large amount of atherothrombotic debris entrapped in the filter could reduce or stop antegrade flow. We present a case of pseudo-no-reflow phenomenon after postdilatation of the stent in a patient with asymptomatic carotid artery stenosis. After several passes using an Export Aspiratio...

Mechanical incorporation of metallic particles in the Sn-Ag-based solder re­ sulted in various intermetallic compound (IMC) morphologies around these particles during reflow. Unlike with the Ni particles, the IMCs formed around Cu and Ag particles are relatively insensitive to reflow profiles employed. The IMC formed around the Ni particles ranges from “sunflower” morphology to “blocky” morphol...

The effects of heparin and the synthetic competitive thrombin inhibitor (2R,4R)-4-methyl-1-[N2-(3-methyl-1,2,3,4-tetrahydro-8-quinolinesulfon yl)-L-arginyl]-2-piperidinecarboxylic acid monohydrate (Argatroban) on thrombolysis with recombinant tissue-type plasminogen activator (rt-PA) was studied in groups of six or seven rabbits with arterial thrombosis. The model consisted of a whole-blood clo...

Background Radiofrequency (RF) ablation of myocardial tissue is a clinically acceptable therapy for atrial fibrillation and ventricular tachycardia. LGE-MRI has been used to assess immediately post-ablation RF lesions. It was shown that appearance of acute lesions in LGE-MRI changes with time after contrast injection [1,2]. Dickfeld, et al. [1] studied ventricular RF lesions delivered epicardia...

OBJECTIVES The purpose of this study was to assess early temporal changes in myocardial perfusion pattern by myocardial contrast echocardiography (MCE) and their relation to myocardial viability in patients with reperfused acute myocardial infarction (AMI). BACKGROUND Myocardial contrast echocardiography no-reflow is associated with poor contractile recovery after AMI. However, little is know...

Recent evidence shows that circulating granulocytes play an important role in capillary stasis and tissue injury. We investigated two aspects of the problem in a Wiggers hemorrhagic shock model of the rat: the survival rate and the microvascular no-reflow phenomenon. A conventional group of rats with normal blood cells and a neutropenic group of rats pretreated with intraperitoneal antigranuloc...

Using our previously reported "thalamic infarction model in the dogs", it was found that hemorrhagic infarction can be produced at a high frequency following recirculation after 6-12 hours of vascular occlusion. In the present study, in order to elucidate the pathophysiology of hemorrhagic infarction, we have undertaken a study of the relations among the histological findings, degree of ischemi...

OBJECTIVES ST segment elevation myocardial infarction (STEMI) is an important cause of the morbidity and mortality in coronary artery disease. The aim of this study is to investigate the relationship between hematologic parameters and post primary PCI coronary no-reflow. PATIENTS AND METHODS A total of 145 consecutive STEMI patients (mean age=58.2±12.3 years) and healthy volunteer admitted wi...