This paper proposes four metrics to measure sprawl in metropolitan regions as marginal changes in land use over time. The metrics (change in urban housing unit density, marginal land consumption per new urban household, housing unit density in newly urbanized areas and percent of new housing units located in previously developed areas) are computed for all 329 metropolitan areas in the continen...

Minimal absent words (MAW) of a genomic sequence are subsequences that are absent themselves but the subwords of which are all present in the sequence. The characteristic distribution of genomic MAWs as a function of their length has been observed to be qualitatively similar for all living organisms, the bulk being rather short, and only relatively few being long. It has been an open issue whet...

  We consider the two well knownminimax and minisum single facility location problems in the plane which has been divided into two regions, and by a straight line. The two regions are measured by various norms . We focus on three special cases in which the regions and are measured by and norms, and block norms, two distinct block norms. Based on the properties of block norms then we use linear ...

The translation of many maternal mRNAs is regulated by dynamic changes in poly(A) tail length. During maturation of Xenopus oocytes, polyadenylation is mediated by three different cis elements in the 3' untranslated region (UTR) of maternal mRNAs. In this issue, Piqué et al. (2008) explore the interplay of these elements to elucidate a combinatorial code that predicts the timing of polyadenylat...

We study the length distribution of a particular class of DNA sequences known as the 5' untranslated regions exons. These exons belong to the messenger RNA of protein coding genes, but they are not coding (they are located upstream of the coding portion of the mRNA) and are thus less constrained from an evolutionary point of view. We show that in both mice and humans these exons show a very cle...

A second case has been found of a nematode gene involved in developmental timing that encodes a short, non-coding RNA. Both RNAs are expressed at specific times and appear to repress target genes by interacting with their 3' untranslated regions. A coincidence? Or does this pathway attract small RNA regulators?

In the late 1960s Brazil began a process of metropolization, especially in its southern region. Migration has often been cited as one of the major reasons for the high rates of population growth in large urban areas, with most of the immigrants having come from the northeastern and southern regions of the country. This physical and demographic process has been a question of concern for various ...

Key Findings. (1) Hospital network participation from 2007 to 2012 increased in larger hospitals (more than 150 beds), non-government not-for-profit hospitals, and metropolitan hospitals. Network participation changed inconsistently in other types of hospitals. (2) Hospital system affiliation has generally increased in hospitals of all sizes, non-government not-for-profit hospitals, hospitals i...