Abstract Background Relapsed acute myeloid leukemia (AML) is associated with the acquisition of additional somatic mutations which are thought to drive phenotypic adaptability, clonal selection and evolution leukemic clones during treatment. We performed high throughput exome sequencing matched presentation relapsed samples from 6 cytogenetically normal AML (CN-AML) patients treated standard re...

conclusion we believed that the nonspecific clinical and laboratory finding of the present case and also the rarity of disease in our area especially in immunocompetent patients made his diagnosis confounding. patient we report an immunocompetent 43 years old iranian man who was in excellent health status until 3 weeksbefore hospitalization when he developed headache. he experienced a 5-week de...

G. Alan Marlatt, Ph.D. is Professor of Psychology and director of the Addictive Behaviors Research Center where he conducts training and research on the prevention and treatment of alcohol and other addictive behavior problems in college students and Native American Youth as well as on the effects of Vipassana meditation on relapse and general well-being. He received his Ph.D. in psychology fro...

Purpose: To ascertain the role of social support and positive affect in prediction of addiction relapse. Materials and Methods: The research method was a causal-comparison. Population included all the clients seeking for medical advice in the centers for Addiction Treatment in Saravan and Iranshar. The sample includes 186 participants (83 participants had no relapse and 83 participants had...