نتایج جستجو برای: relapsed hodgkin lymphoma
تعداد نتایج: 117560 فیلتر نتایج به سال:
Although previously characterized as a subtype of diffuse large B-cell lymphoma, primary mediastinal lymphoma (PMBCL) is now recognized distinct NHL with unique clinical and biologic features, many which overlap classic Hodgkin lymphoma. PMBCL has peak incidence in the adolescent young adult (AYA) population and, unlike other subtypes NHL, higher among females. Recent studies into molecular bio...
SAR3419 is a novel anti-CD19 humanized monoclonal antibody conjugated to a maytansine derivate through a cleavable linker for the treatment of B-cell malignancies. SAR3419 combines the strengths of a high-potency tubulin inhibitor and the exquisite B-cell selectivity of an anti-CD19 antibody. The internalization and processing of SAR3419, following its binding at the surface of CD19-positive hu...
background: primary pancreatic lymphoma (ppl) is a rare condition and its differentiation from most commonly adenocarcinoma is very important because of different prognosis and treatment strategies. the aim of this study was presenting different aspects for differentiating ppl from pancreatic adenocarcinoma. materials andmethods: during 14 months, 5 patients who underwent endoscopic ultrasonogr...
the occurrence of langerhans cell histiocytosis (lch) in a patient with lymphoma is an indication of a probable relationship between them. the two conditions have similarities both clinically and histopathologically. occurrence of these two conditions in the same patient, particularly not simultaneously, is rare. according to different management and treatment of these conditions, exact histopa...
Recent advances in Hodgkin lymphoma research are expected to prelude a promising new treatment era for patients and their treating physicians. Scientific investigations over the last few years have provided new insights into risk stratification, and, simultaneously, a plethora of novel targeted therapies are emerging for patients with relapsed and refractory disease. These novel therapies will ...
PURPOSE Inotuzumab ozogamicin (INO) is an antibody-targeted chemotherapy agent composed of a humanized anti-CD22 antibody conjugated to calicheamicin, a potent cytotoxic agent. We performed a phase I/II study to determine the maximum-tolerated dose (MTD), safety, efficacy, and pharmacokinetics of INO plus rituximab (R-INO) for treatment of relapsed/refractory CD20(+)/CD22(+) B-cell non-Hodgkin ...
Introduction: We analyzed the incidence, risk factors of central nervous system (CNS) relapse and outcome CNS involvement in patients with peripheral T-cell lymphomas (PTCL) prospectively observed Czech Lymphoma Study Group Registry (NCT03199066). Methods: Out 1040 we identified 29 (2.79%) involvement: 13 (1.25%) had disease at initial diagnosis 16 (1.54%) relapse. Median age was 61 years 54.5 ...
common radiologic features of lymphoma in lung are included: adenopathy, pleural effusion, multiple or solitary masses and diffuse infiltration. we want to present a 28y/o male with pulmonary hodgkin lymphoma with a rare radiographic pattern and distinct histologic description that at first misdiagnosed as pulmonary tuberculosis but eventually lung biopsy confirmed diagnosis of pulmonary hodgki...
OBJECTIVE Classical Hodgkin lymphoma shows a peak incidence at 15-35 years, and a second peak in elderly patients; however, pathological characteristics of elderly patients with classical Hodgkin lymphoma have not been analyzed enough. METHODS In a total of 154 patients with classical Hodgkin lymphoma, we analyzed the clinicopathological characteristics of classical Hodgkin lymphoma patients ...
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