نتایج جستجو برای: related deficiencies
تعداد نتایج: 1186144 فیلتر نتایج به سال:
Mitochondrial dysfunction is commonly observed in degenerative disorders, including Alzheimer's and Parkinson's disease that are characterized by the progressive and selective loss of neuronal subpopulations. It is currently unclear, however, whether mitochondrial dysfunction is primary or secondary to other pathogenic processes that eventually lead to age-related neurodegeneration. Here we est...
Eighty-eight percent of countries face the serious burden malnutrition either two or three forms, such as acute and/or chronic undernutrition, micronutrient deficiencies, obesity, and diet-related diseases (including type II diabetes, cardiovascular diseases, certain types cancer) [...]
The basic physiology of leucocyte emigration from the intravascular space into the tissues is now known to be dependent on a class of cell surface molecules that have come to be known as adhesion molecules. Many cell-cell interactions are dependent on adhesion and signal transduction via the various adhesion molecules, particularly the integrins. The study of the functions of these molecules ha...
Mice deficient for endothelial nitric oxide synthase (NOS3(-/-)) may represent a good model for studying embryo loss and intrauterine growth retardation caused by vascular deficiencies. We determined the effects of embryo genotype (homozygous vs. heterozygous descendants with paternal or maternal source of the non-functional NOS3 allele) and maternal environment (NOS3(-/-) vs. wild-type NOS3(+/...
Formal Safety Assessment (FSA) is the premier scientific method that is being currently used for the analysis of maritime safety and for the formulation of related regulatory policy. This paper conducts a critical review of the FSA methodology and proposes ways to improve it. All steps of the FSA approach are looked at and possible pitfalls or other deficiencies are identified. Then proposals a...
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