Gluten related disorders a range of inflammatory disorders of the small intestine characterized by malabsorption after ingestion of gluten in individuals with a certain genetic background. Clinical presentation can vary from full-blown malabsorption to subtle and atypical symptoms. Diagnosis currently relies on clinicopathologic studies including mucosal biopsy, serologic tests, and the effects...

The ongoing COVID-19 pandemic urgently requires the availability of interventions that improve outcomes for those with severe disease. Since SARS-CoV-2 infection is characterised by dysregulated lung mucosae, and mucosal homeostasis heavily influenced IL-13 activity, we explore recent findings indicating production proportional to disease severity. Read more at jctres.com

Gastrointestinal lymphomas can occur in nodular, polypoid, cavitary, ulcerative or diffuse infiltrating (submucosal) forms. Barium studies and computed tomography (CT) are the most popular imaging techniques used to diagnose these lymphomas. Barium studies are superior to CT in evaluating mild mucosal and submucosal changes. However, CT is the technique of choice because it provides a complete ...

Background and study aim: Duodenal mucosal lesions are usually difficult to diagnose. White light endoscopy(WLE) ‎generally does not visualize the duodenal villous patterns properly miss small ‎elevated lesions, which result in an inaccurate diagnosis. We aimed assess ‎diagnostic accuracy of I-scan technology for evaluation histological confirmation ‎mucosal duodenum its role biopsy targeting‎....

BACKGROUND Several oral mucosal abnormalities have been reported to occur more frequently in patients with liver disease. It has, however, not been determined if these conditions are related to the disease or are manifestations of extraneous factors not associated with the liver pathology. OBJECTIVE To identify and quantify oral abnormalities in candidates for liver transplantation, and to de...

Background and aim: Vitiligo is an acquired idiopathic hypomelanotic disease. The purpose of this study was to review clinical characteristics of vitiligo and their significance in the progression of vitiligo.Materials and methods: Eight hundreds and sixteen cases of vitiligo were studied from February 2005 to October 2006. All of the patients were referred to dermatolo...

Physiologic stress associated with illness and hospitalization is known to result in gastrointestinal ulceration, especially among the critically ill. The complication of this stress-related mucosal disease could be prevented with appropriate application of pharmacologic prophylaxis. Vigilance by the nursing staff is required to properly detect and manage the condition.

Background: A clinicopathological study of 75 cases of pemphigus was carried out at Saurashtra region of Gujarat State, India. This study was done to subtype this disease with evaluation of clinical and histopathological presentation. Methods: The study was carried out in a two-year period at skin department of Guru Gobind Singh Hospital, Jamnagar. Seventy five patients of pemphigus were examin...

Primary malignant melanoma of the oral cavity is a rare neoplasm. The tumors tend to metastasize or locally invade tissue more readily than other malignant tumors in the oral region. The survival of patients with mucosal melanomas is less than for those with cutaneous melanomas. Tumor size and metastases are related to the prognosis of the disease. Early detection, therefore, is important.