Total number of abortions: 30,699.  60% of abortions were criminal and the re- mainder were due to:  (a)Cervical incompetence  (b) hypothyr oidism (c) Listeriosis (d) Toxoplasmosis (e) Luteal phase deficiency (f) Placental deficiency Mg) Rh and ABO incompatibility and unknown etiology.  Therapeutic abortions were also performed in several cases due to:  (a) Miliary tube...

Recent developments in genetics and molecular biology have led to an increased understanding of the pathobiology of renal cancer. Thorough knowledge of the molecular pathways associated with renal cancer is a prerequisite for novel potential therapeutic interventions. Studies are ongoing to evaluate novel anticancer agents that target specific molecular entities. This article reviews current kn...

Germline mutations of FH, the gene that encodes for the tricarboxylic acid TCA (TCA) cycle enzyme fumarate hydratase, are associated with an inherited form of cancer referred to as Hereditary Leiomyomatosis and Renal Cell Cancer (HLRCC). Individuals with HLRCC are predisposed to the development of highly malignant and lethal renal cell carcinoma (RCC). The mechanisms of tumorigenesis proposed h...

Occurrence of multiple primary malignant tumors is very uncommon .Co occuring can be synchronous or non synchronous.Tumors presenting within a period less than equal to 6 months are called and if they occur after termed as metachronous. Synchronous malignancies rarer For defining both the should show criteria malignancy, possibility metastasis must have been ruled out pathologically distinct. B...

Approximately 1,700 cases of renal transplantation are performed annually, and various diseases may occur due to long-term internal use postoperative immunosuppressants. We experienced a case cervical cancer, which is thought be human papillomavirus (HPV)-related after living kidney transplantation, underwent laparoscopic radical hysterectomy.

We report a case of coexisting urothelial cancer and renal tuberculosis in the same kidney. The patient is a 72-year-old female with a remote history of treated pulmonary tuberculosis who presented with haematuria, initial investigation of which elucidated no definitive cause. Almost 1 year later, a diagnosis of metastatic urinary tract cancer was made. The patient received chemotherapy for adv...

The standard therapy for thyroid cancer is total or near total thyroidectomy, followed by the administration of radioactive iodine for remnant ablation or residual disease. Patients with radioiodine therapy are predisposed to second malignant neoplasms in organs such as central nervous system (CNS), breast, prostate, kidney, bone marrow, salivary gland, and digestive tract. Exposure to carcinog...

Cancer is a major health problem and cause of death worldwide that accounted for 7.6 million deaths in 2008, which is projected to continue rising with an estimated 13.1 million deaths in 2030 according to WHO. Breast cancer is the leading cause of cancer-based death among women around the world and its incidence is increasing annually with a similar tendency. In contrast, renal cell carcinoma ...

Lithium induces proliferation in the epithelium of renal collecting ducts. A recent small-scale cohort study reported a strong association between use of lithium and increased risk of renal neoplasia. We therefore conducted a large-scale pharmacoepidemiologic study of the association between long-term use of lithium and risk of upper urinary tract cancer, including renal cell cancer and cancers...

The von Hippel-Lindau (VHL) gene is the major renal cancer gene in adults. The mechanism of renal tumor suppression by VHL protein is only partly elucidated. VHL loss increases expression of the hypoxia-inducible factor alpha transcription factors. However, clinical and biochemical data indicate that the hypoxia-inducible factors are necessary but not sufficient for renal tumorigenesis, which s...