Background: The Presence of donor leukocytes in recipients of organ allograft has been shown even several years after transplantation. However, it remains unclear whether this donor cell microchimerism plays an effective role in allograft acceptance or is simply a consequence of immunosuppressive conditions in recipients. Objective: To study microchimerism in a group of kidney transplant recipi...

oxygen-derived free radical* (ofr) involvement in ischacmia-rcpcrfusion (ir) injury was investigated in a rat isolated kidney model, using 20 minutes iscliaemia followed by 15 or 60 minutes reperfusion. two antioxidants, the xanthine oxidase inhibitor allopurinol and the hydroxyl radical scavenger dimcthylthiourca (dmtu), were uscit to try and prevent ofr-relatcd damage. renal function was esti...

Ultra-marathon running is supposed to increase the parameters of skeletal muscle damage and impair renal function. The purpose of this study was to investigate the effect of branched-chain amino acid supplementation on skeletal muscle damage and renal function during a 100-km ultra-marathon. Twenty-eight athletes were randomly divided into two groups, one group using branched-chain amino acid s...

background: the presence of donor leukocytes in recipients of organ allograft has been shown even several years after transplantation. however, it remains unclear whether this donor cell microchimerism plays an effective role in allograft acceptance or is simply a consequence of immunosuppressive conditions in recipients. objective: to study microchimerism in a group of kidney transplant recipi...

how to cite this article: afsharkhas l, tavasoli a. renal function in children with febrile convulsions.iran j child neurol. 2014 autumn;8(4):57-61. abstract objective febrile convulsions (fc) are the most frequent seizure disorder in children. some studies have detected serum electrolyte disturbances in patients with fc. this study determines serum electrolytes, renal function tests, and frequ...

conclusions: in this study, kidney transplant recipients with a lower ri and pi and a higher edv at 1week showed better graft function at 6 months after transplantation. results: fourteen patients (15.4%) had impaired graft function after 6 months (gfr less than 60 ml/min/1.73m2). multivariate linear regression analysis showed significant correlation between gfr at 6 months and ri, pi and edv w...

Renal failure is a situation in which kidney fails to function adequately. There are two forms of renal failure: acute and chronic. End-Stage renal disease is the final stage of chronic renal failure where there is a progressive, irreversible deterioration in renal function which can be substituted by renal replacement therapy, haemodialysis (HD), peritoneal dialysis, or transplantation. The ai...

INTRODUCTION The aim of the study was to analyse the influence of renal impairment on the pharmacokinetic parameters (PK) of mycophenolic acid (MPA) and its glucuronide metabolite (MPAG) in renal transplant recipients. MATERIAL AND METHODS The study included 43 adult patients during the maintenance period (> 6 months) following renal transplantation, treated with mycophenolate mofetil (MMF), ...