olanzapine is the frequently prescribed drug in children and adolescents with bipolar disorder, but unfortunately it has metabolic side-effects. on the other hand, in a number of melatonin studies on sleep cycle, regulation of metabolic abnormalities has been reported. therefore, we aimed to study effects of melatonin in reducing metabolic side-effects of olanzapine in 11-17 year-old patients w...

Background Among all malignances, leukemia has the greatest effects on patients 'psychological aspects. Anxiety is common problem in leukemia patients (especially in children). Since no study has addressed the effect of Slow-stroke back massage (SSBM) on anxiety in the pediatrics with chronic leukemia, this investigation aimed to controlling anxiety through a non-drug method (such as SSBM) in c...

Bachground: Today, some treatments like neurofeedback and Vitamin D Supplementation are of great importance in treatment of Attention-Deficit/Hyperactivity Disorder (ADHD). Present literature showed efficacy each of them. For determination of efficacy of combined treatment, this study aims to compare the efficacy of each of them with combined neurofeedback and vitamin D supplementation in the t...

conclusions this study indicated that the delivery rate accuracy of elastomeric infusion pumps is preserved after repeated usage. these laboratory findings suggested that elastomeric pumps could be safely refilled in the successive days to provide postoperative analgesia. results the mean flow rate in the three series of measurements showed a gradual increase; however, the difference was not st...

The exploratory behaviour of laboratory rodents is of interest within a number of areas of behavioural pharmacology. However, how best to measure exploratory behaviour in rodents remains a contentious issue. Many unconditioned tests, such as the open field, potentially confound general locomotor activity with exploration. The hole-board apparatus appears to avoid this confound, as head-dipping ...

background: the prognosis of patients with decompensated cirrhosis due to hepatitis b is very poor. it has been shown that lamivudine can improve liver function and delay the need for liver transplantation in hbeag-positive patients with decompensated cirrhosis. however, information regarding long-term use of lamivudine in hbeag-negative patients with cirrhosis is limited. the primary objective...

abstract background: most of the patients admitted in the intensive care units (icus) require an endotracheal tube and mechanical ventilation. in order to clear and maintain patency of the airways, endotracheal suctioning is required. therefore, the least detrimental way of endotracheal tube suctioning which can diminish the complications should be selected. the present study aimed to compare t...