The Ross et al. paper describes the creation of an inbred, transgenic mini-pig that carries a mutant human rhodopsin gene which is expressed in the retina and is associated with progressive loss of light-evoked ERG responses. This is a significant achievement of considerable practical value in an era in which translational activity for retinal diseases is burgeoning. The rationale for generatin...

String matching is the problem of finding all occurrences of a given pattern in a given text. It is an extensively studied problem in computer science because of its direct application to several areas such as text, image and signal processing, speech analysis and recognition, data compression, information retrieval, computational biology and chemistry. Since 1970 more than 85 string matching a...

A difficulty with research in computational design methods is in evaluating the capabilities and merit of the fundamental research output beyond initial benchmark tests that compare to theoretical examples. While this is a necessary step in method development, issues involving integration of computational methods within the design process are often overlooked. This need for better integration o...