Thermo-responsive adsorbents for immunoglobulin G (IgG) employing ε-polylysine (EPL) as a polymer backbone were developed. The introduction of mercaptoethylpyridine (MEP) as an IgG-binding ligand and hydrophobization of side chains afforded thermo-responsive IgG adsorbents, whose thermo-responsive IgG desorption ratio was up to 88% (EPL/MEP derivative 3m). The changes in surface densities of ac...

The use of self-assembled nanoparticles for drug delivery has received significant attention in recent years. However, the dynamic nature polymeric systems means there is a need to develop greater understanding inherent stability these systems. In particular, if materials remain as discrete nanoparticles, or exchange material between particles critical. Herein, we labelled pH-responsive with fl...