The restless legs syndrome (RLS) is a common neurological disorder to take possession of increasing attention. RLS is characterized by an urge to move the legs, usually accompanied by uncomfortable or unpleasant sensations, that occurs or worsen at rest and is relieved by activity. The symptoms of RLS have a major impact on nocturnal sleep and daytime functions. The clinical diagnostic criteria...

Sleep problems are more common in patients with renal failure compared to populations without overt severe comorbidities. Both central and obstructive forms of sleep disordered breathing (SDB) are present in patients with renal failure [1, 2]. Other sleep problems, including restless leg syndrome, periodic limb movement syndrome and insomnia, also occur at high rates in this population. As the ...

Purpose Restless Leg Syndrome (RLS), a common sleep disorder, has been linked to increased cardiovascular disease (CVD) risk, key components of the metabolic syndrome, and is associated with significant societal and economic burden. Current treatments are often ineffective and can have serious side effects, highlighting the need to investigate promising new non-pharmaceutical approaches. In thi...

Limited research suggests a relationship between restless legs syndrome and hypertension. We, therefore, assessed the relationship between restless legs syndrome and hypertension among middle-aged women. This is a cross-sectional study including 65 544 women (aged 41-58 years) participating in Nurses' Health Study II. The participants with diabetes mellitus and arthritis were excluded, because ...

and commentary also appear in ACP Journal Club. Therapeutics EBM Volume 8 July/August 2003 117 www.evidence-basedmedicine.com

Restless legs syndrome (RLS) is a disease characterized by the presence of an urge to move the legs accompanied by unpleasant sensations in the legs. The symptoms appear or increase in the evening and during the night, they are provoked by rest, and are totally or partially relieved by moving the legs [1, 2] . Diagnosis of RLS is based solely on the presence of the abovementioned symptoms witho...

Introduction: Restless legs syndrome is a sensory-motor disorder that causes sleep disorder. The syndrome in patients undergoing hemodialysis has to do with depression, sleep deprivation, performance disorder, day fatigue, excessive daytime sleepiness, stress and anxiety, and increased risk of cardiovascular diseases. The objective of this systematic meta-analysis study was to estimate prevalen...

BACKGROUND Restless leg syndrome (RLS) is defined as an uncomfortable feeling in the limbs which is prominently sensed in legs. Dopamine system involvement is considered as the base of RLS's etiology. Because of safety, anti-oxidant and dopaminergic promoting action of selenium, this study aims to investigate the effect of selenium on restless leg syndrome treatment. METHODS Sixty patients wi...

Restless legs syndrome (RLS) is a common condition that is frequently unrecognized, misdiagnosed and poorly managed. It is characterized by uncomfortable sensations deep in the legs developing at rest that compel the person to move; symptoms are worst at night and sleep disturbance is common. RLS occurs in 7%-11% of the population in Western countries, and many such people experience troublesom...