Alpha 1 antitrypsin deficiency predisposes subjects to developing pulmonary emphysema and childhood liver cirrhosis. We have studied restriction fragment length polymorphisms (RFLPs) of the alpha 1 antitrypsin gene in a normal population and a group of patients with pulmonary emphysema. We have identified five RFLPs with eight restriction enzymes. The most frequent polymorphisms have been detec...

Fifty-one strains representing Xanthomonas campestris pv. manihotis and cassavae and different pathovars occurring on plants of the family Euphorbiaceae were characterized by ribotyping with a 16S+23S rRNA probe of Escherichia coli and by restriction fragment length polymorphism analysis with a plasmid probe from X. campestris pv. manihotis. Pathogenicity tests were performed on cassava (Maniho...

Several studies have focused on polymorphisms of major histocompatibility complex (MHC) in sheep, Ovar-MHC. This molecule plays a pivotal role in antigen presentation for eliciting immune responses against invading pathogens. The best-characterized genetic control of disease resistance and immune response in animals is associated with MHC. Numerous molecular genetic investigations have been und...

several asthma susceptibility loci, including a region containing the vitamin d receptor (vdr) gene located at chromosome 12q, have been identified using genome-wide screens. our aim is to investigate the association between single nucleotide polymorphisms (snps) in vdr gene and asthma. one hundred one asthma patients and 206 healthy controls were enrolled in this study. genotypes were determin...

background and objectives: avian tuberculosis is one of the most important infections affecting most species of birds. mycobacterium avium can not only infect all species of birds, but also infect some domesticated mammals.the most crucial aspect of control and eradication scheme is identification of infection sources and transmission routs. mo- lecular techniques such as restriction fragment l...

objective(s):leptin receptor (lepr) is a member of the class i cytokine receptor super-family that is known implicated in the initiation and progression of breast cancer. we have investigated the effect of q223r polymorphism on the breast cancer susceptibly in a sample of iranian subjects. materials and methods:we utilized a polymerase chain reaction (pcr) restriction fragment length polymorphi...