This study reports on the development and initial psychometric properties of the Children's Saving Inventory (CSI), a parent-rated measure designed to assess child hoarding behaviors. Subjects included 123 children and adolescents diagnosed with primary Obsessive-Compulsive Disorder (OCD) and their parents. Trained clinicians administered the Children's Yale-Brown Obsessive-Compulsive Scale (CY...

This paper introduces three novel techniques for updating the invertible representation of the basis matrix when solving practical sparse linear programming (LP) problems using a high performance implementation of the dual revised simplex method, being of particular value when suboptimization is used. Two are variants of the product form update and the other permits multiple Forrest-Tomlin upda...

The primary mission and purpose of the Board is to enforce public policy related to the safe and effective practice of nursing in the interest of public welfare. As a regulatory agency of state government, the Board of Nursing accomplishes this mission as authorized by Kentucky Revised Statutes (KRS) Chapter 314—The KENTUCKY NURSING LAWS and attendant administrative regulations. In accomplishin...

This study had three objectives: first, to investigate the relative importance of mindfulness facets negative affect (NA) among patients with chronic pain; second, test monitor and acceptance theory that observing is associated lower NA only if occurs in an accepting manner; third, relation between obsessive–compulsive symptoms (OCS). One hundred nineteen musculoskeletal pain completed Five-Fac...

In recent years, there has been a considerable increase in the development of assessment tools for obsessive-compulsive symptomatology in children and adolescents. The Obsessive Compulsive Inventory-Child Version (OCI-CV) is a well-established assessment self-report, with special interest for the assessment of dimensions of Obsessive Compulsive Disorder (OCD). This instrument has shown to be us...

Lin28A is a highly conserved RNA-binding protein that concurs to control the balance between stemness and differentiation in several tissue lineages. Here, we report the role of miR-128a/Lin28A axis in blocking cell differentiation in acute myeloid leukemia (AML), a genetically heterogeneous disease characterized by abnormally controlled proliferation of myeloid progenitor cells accompanied by ...

objective: recent studies have emphasized the important role of cognitive beliefs in etiology and ‎maintenance of obsessive-compulsive disorder (ocd). ocd has different subtypes, but the ‎specific role of cognitive beliefs in ocd symptomatology is not clear. the aim of the current ‎study was to determine whether the cognitive factors proposed by obsessive compulsive ‎cognitions working group (o...

Obsessive-compulsive disorder is characterized by the presence of recurrent and persistent thoughts, urges or images as well as repetitive behaviors or mental acts. According to the existing evidence, it can be predicted that difficulties in emotion regulation, impulsivity and anger are related to obsessive-compulsive disorder in one way or another. The aim of the present study was to predict o...

BACKGROUND DNMT3A mutations are frequently discovered in acute myeloid leukemia (AML), associated with poor outcome. Recently, a relapse case report of AML extramedullary disease has showed that AML cells harboring DNMT3A variation were detected in the cerebral spinal fluid. However, whether a causal relationship exists between DNMT3A mutation (D3Amut) and extramedullary infiltration (EMI) is u...

The recently characterized immunotoxin HuM195-gelonin consists of a humanized anti-CD33 monoclonal antibody conjugated to the single-chain plant toxin gelonin. Binding of the immunotoxin to hematopoietic cells that express the CD33 differentiation antigen has been demonstrated and results in cytotoxicity due to ribosomal inactivation by gelonin. Blast cells from most patients with acute myeloge...