نتایج جستجو برای: rhob

تعداد نتایج: 449  

2012
Beata Wojciak-Stothard Lan Zhao Eduardo Oliver Olivier Dubois Yixing Wu Dimitris Kardassis Eleftheria Vasilaki Minzhou Huang Jane A. Mitchell Louise S. Harrington George C. Prendergast Martin R. Wilkins

Journal: :Journal of Biological Chemistry 2002

Journal: :The American Journal of Human Genetics 2007

Journal: :Journal of Biological Chemistry 2001

2017
Nikola Arsic Alexandre Ho-Pun-Cheung Crapez Evelyne Eric Assenat Marta Jarlier Christelle Anguille Manon Colard Mikaël Pezet Pierre Roux Gilles Gadea

The TP53 gene plays essential roles in cancer. Conventionally, wild type (WT) p53 is thought to prevent cancer development and metastasis formation, while mutant p53 has transforming abilities. However, clinical studies failed to establish p53 mutation status as an unequivocal predictive or prognostic factor of cancer progression. The recent discovery of p53 isoforms that can differentially reg...

Journal: :Scientific reports 2016
Robert Bzymek Markus Horsthemke Katrin Isfort Simon Mohr Kerstin Tjaden Carsten Müller-Tidow Marlies Thomann Tanja Schwerdtle Martin Bähler Albrecht Schwab Peter J Hanley

We recently found that macrophages from RhoA/RhoB double knockout mice had increased motility of the cell body, but severely impaired retraction of the tail and membrane extensions, whereas RhoA- or RhoB-deficient cells exhibited mild phenotypes. Here we extended this work and investigated the roles of Rho signaling in primary human blood monocytes migrating in chemotactic gradients and in vari...

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