The present study proposes a simple and inexpensive photometric method for the selective determination of Ag(I). This employed home-made double beam photometer silver ions based on an optode sensor prepared by immobilization 5-(P-Dimethylaminobenzylidene)-rhodanine (PDR) triacetyl cellulose (TAC) membrane. Two green LEDs as sources light light-dependent resistors (LDRs) detectors were used in p...

Mannich reaction was applied between 4-fluorobezaldehyde, selected acetophenone and several anilines, catalyzed by silica sulfuric acid for the synthesis of β-amino carbonyl derivatives. Reaction time and yield of the products depended on the nature of acetophenone and aniline subsituents. Using aliphatic amines instead of aromatic amines under same reaction conditions, afforded aldol condensat...

Due to the rapidly growing bacterial resistance to antibiotics and the scarcity of novel agents under development, bacterial infections are still a pressing global problem, making new types of antibacterial agents, which are effective both alone and in combination with traditional antibiotics, urgently needed. In this paper, seven series of N-arylsulfonylindole analogs 5-11 bearing rhodanine mo...

During the last few decades, Multi-Component Reactions (MCRs) have been studied as a facile route to assemble complex important structures in a small number of steps, while reducing production costs and environmental concerns. As a result, MCRs have attracted growing attention, leading to the development of new, highly selective methods for the synthesis of bioactive compounds such as natural p...

2-(Thiophen-2-yl)thiazole was introduced as a π-bridge into diethylamino coumarin and novel coumarin sensitizers were synthesized with cyanoacrylic acid or rhodanine acetic acid as electron acceptor. Their light-harvesting capabilities and photovoltaic performance were investigated and compared with those of a similar sensitizer bearing a phenylthiophene bridge. Replacement of benzene in the π-...

Some [(5Z)-(5-arylalkylidene-4-oxo-2-thioxo-1,3-thiazolidin-3-yl)]acetic acids were prepared as potential antifungal compounds. The general synthetic approach to all synthesized compounds is presented. Lipophilicity of all the discussed rhodanine-3-acetic acid derivatives was analyzed using a reversed phase high performance liquid chromatography (RP-HPLC) method. The procedure was performed und...

Poly(ADP-ribosyl)ation is a reversible post-translational protein modification involved in the regulation of a number of cellular processes including DNA repair, chromatin structure, mitosis, transcription, checkpoint activation, apoptosis and asexual development. The reversion of poly(ADP-ribosyl)ation is catalysed by poly(ADP-ribose) (PAR) glycohydrolase (PARG), which specifically targets the...