Objective(s): Angiotensin Ⅱ type 1 receptor blockers (ARBs) represent one of the widely used antihypertensive agents. In addition to anti-hypertension effect, some ARBs also show other molecular effects such as activating peroxisome proliferator-activated receptor-γ and so on. Here we studied the effects of telmisartan on the rat isolated mesenteric artery rings pre-contracted by phenylephrine ...

let r be a commutative ring and m be an r-module. we say that m is fully primary, if every proper submodule of m is primary. in this paper, we state some characterizations of fully primary modules. we also give some characterizations of rings over which every module is fully primary, and of those rings over which there exists a faithful fully primary module. furthermore, we will introduce some ...

In this study, the possible involvement of L-type voltage-operated calcium channels in the vasorelaxant effect of the flavonoid quercetin was investigated, using the isolated aortic rings from normal male rats. Addition of quercetin (0.1 µM-1 mM) caused a significant dose-dependent relaxation of noradrenaline (NA)- and KCl-preconstricted rings and nifedipine attenuated this response, especially...

In this paper, crashworthiness characteristics of conical steel tubes stiffened by annular rings and rigid polyurethane foam are investigated. For this purpose, wide circumferential rings are created from the outer surface of the conical tube at some determined areas along tube length. In fact, this method divides a long conical tube into several tubes of shorter length. When this structure is ...

To evaluate the acute effect of lovastatin on diabetic endothelial dysfunction, we examined this effect on the aortic rings of streptozotocin-diabetic rats. The endothelial function was assessed in aortic rings isolated from diabetic rats, 12 weeks after treatment with streptozotocin (45 mg/kg, i.p.). The concentration-response curve to acetylcholine (Ach) in the aortic rings precontracted with...

In this study, on the combination of chlorpromazine with two aromatic rings, halogens are attached to the rings, and changes in the angles and lengths of the ipsos are calculated. Calculations show that by changing the halogen based on the amount of electronegativity, the magnitude and variation of the angular lengths The lengths of the links also change in the following order. The angles of th...

nanopartmles have been used as an approach to improve the pharmacodynamic and phannacokinetie propertiesof various drues. amino acids have been considered to be useful to make such nano particles because ofthocompatithe and biodegradable characteristic. the quantum mechanical method that was chosen to analyze inethio hexa peptide nano ring]. the structure of some peptide nanorrigs as well as th...

introduction radiofrequency planar microcoils are used to increase the resolution of magnetic resonance images of small samples. in this study, we aimed to design and fabricate a spiral planar microcoil constructed on a double-sided printed circuit board (pcb). it has four rings with an internal diameter of 241 microns tuned and matched at 63.8 mhz. materials and methods to achieve the maximum ...

‎We call a ring $R$ right generalized semiperfect if every simple right $R$-module is an epimorphic image of a flat right $R$-module with small kernel‎, ‎that is‎, ‎every simple right $R$-module has a flat $B$-cover‎. ‎We give some properties of such rings along with examples‎. ‎We introduce flat strong covers as flat covers which are also flat $B$-covers and give characterizations of $A$-perfe...