to compare the effects of topiramate versus valproate sodium as an add-on therapy to a combination of lithium and risperidone (li+ris) on body weight and serum lipid profile in children and adolescents with bipolar disorder.in a single-blind randomized clinical trial, thirty children and adolescents with bipolar disorder type i in the manic or mixed phase, treated with the combination of li+ris...

RIS is a New Delhi-based autonomous policy think-tank supported by the Government of India and devoted to trade and development issues. Its work programme focuses on policy research and capacity building on multilateral trade and financial negotiations, regional economic cooperation in Asia, South-South cooperation, new technologies and development, and strategic policy responses of developing ...

Broadband Railway Digital Network (BRDN) integrating the emerging broadband wireless access technologies will satisfy the requirements of next generation Railway Information System (RIS). This paper proposes an overall implementation scheme for BRDN with discussion on its main components, such as the intranet on train, train-ground internetworking and infrastructure of BRDN. The paper aims at e...

Treatment options for localized resectable basal cell carcinoma (BCC) include micrographically controlled surgery, simple excision, curettage, laser ablation, cryosurgery, imiquimod, 5-fluorouracil, photodynamic therapy and radiotherapy. The aim of this study was to assess the preferences of patients with BCC for outcome (cure and recurrence rate, cosmetic outcome, risk of temporary and permane...

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Cytochrome P450 induction-mediated drug-drug interaction (DDI) is one of the major concerns in clinical practice and for the pharmaceutical industry. Previously, a novel approach [the relative induction score (RIS)] was developed using the Fa2N-4 immortalized human hepatocyte line and proposed as a tool for predicting magnitude of clinical DDIs caused by induction of CYP3A. The approach is base...

Objective. The guidelines of the American Thyroid Association (ATA) recommend an upper limit reference interval (RI) of thyroid stimulating hormone (TSH) of 2.5 mIU/L in the first trimester of pregnancy and 3.0 mIU/L in subsequent trimesters, but some reported ranges in China are significantly higher. Our study aimed to establish trimester- and assay-specific RIs for thyroid hormones in normal ...

Lambs were used to evaluate the effect of acute heat stress (HS) or restraint and isolation stress (RIS) on endocrinological and immunological functions. In Exp. 1, lambs were exposed to HS (35 degrees C) and control lambs (CN) were exposed to 21 degrees C for 24 h in two replicates (n = 8 lambs total per treatment). Samples of serum were obtained at frequent intervals for evaluation of cortiso...

The aim of this study was to establish reference intervals (RIs) for the hemogram and iron status biomarkers in a physically active population. The study population included male volunteers (n = 150) with an average age of 19 ± 1 years who had participated in a regular and controlled exercise program for four months. Blood samples were collected to determine hematological parameters using a Sys...