BACKGROUND Constraint-induced movement therapy (CIMT) is an effective treatment for upper extremity (UE) recovery post stroke. Difficulties implementing a traditional CIMT approach have led to development of protocols featuring varying practice schedules, including a 10-week, 3 times per week intervention, termed modified CIMT (mCIMT). To date, systematic reviews of CIMT have grouped the variou...

BACKGROUND Limited data are available about the effectiveness of early rehabilitation after stroke. OBJECTIVE This is the 1st randomized controlled trial of constraint-induced movement therapy (CIMT) in subacute stroke to investigate neurophysiologic mechanisms and long-term outcome. METHODS Within 2 weeks after stroke, 23 patients with upper extremity (UE) weakness were randomized to 2 wee...

Amidst growing concerns over the spread of antibiotic-resistant Staphylococcus aureus strains, the identification of alternative therapeutic molecules has become paramount. Previously, we utilized a Caenorhabditis elegans-S. aureus screening platform to identify potential anti-infective agents from a collection of natural extracts and synthetic compounds. One of the hits obtained from the scree...

In this paper, we consider an estimation problem about the tensor coefficient in a regression model with multiple and unknown change-points. We generalize some recent findings five ways. First, studied is more general than one context of matrix parameter Second, develop asymptotic results estimators Third, construct class shrinkage that encompasses unrestricted estimator (UE) restricted (RE). F...

We thank Drs Stinear and Byblow for their kind words. These authors identified a compelling message regarding patient strati-fication from Figure 2 of our prior report: specific ranges of upper extremity (UE) Fugl–Meyer (FM) scores correspond to distinct UE functional states (see below). This approach provides a Rosetta Stone, whereby examination assessments are expressed in terms that are clin...

The underground economy (UE) also known as the shadow economy is a phenomenon known throughout the world. The growth of the UE is a matter of increasing concern, at least, throughout the developed nations. Researchers have recognized that the underground economy and crime are linked. Studies on the US, Canada and the transition economies indicate that crime and the shadow economy are facts of l...

[Purpose] The aim of this study was to determine the effect of spatial target reaching training (TRT) based on visual biofeedback (VB) on the upper extremity (UE) function of hemiplegic subjects. [Subjects and Methods] Forty subjects between six and eighteen months post-stroke were enrolled in this study. They were randomly allocated to an experimental group (EG, n=20) and a control group (CG, ...

Upper extremity (UE) hemiparesis persists after stroke, limiting hand function. Neuromuscular electrical stimulation (NMES) is an effective intervention to improve UE recovery, although the underlying mechanisms are not fully understood. Our objective was to establish a reliable protocol to measure UE agonist-antagonist forearm monosynaptic reflexes in a pilot study to determine if NMES improve...

We report the identification and purification of a yeast factor functionally homologous to the human upstream element factor (UEFh). Although the yeast protein (UEFy) has a higher molecular weight than the HeLa UEF (60 kD versus 45 kD) both have identical DNA-binding properties: the purified UEFy recognizes the Adenovirus 2 (Ad2) major late promoter upstream element (MLP-UE; from nucleotide -49...

OBJECTIVES This work aimed to enhance anti-skin cancer activities of Apostichopus japonicus, spiky sea cucumber, through ultrasonification extraction process at low temperature. METHODS Dried Apostichopus japonicus was extracted with an ultrasonification process at 50°C and 95 kHz for two hours (UE), and anti-skin cancer activities of the extract from the UE were also compared with those from...