objectives: the aim of this randomized clinical trial was to assess the efficacy of stimdate compared to ritalin in the treatment of children with attention deficit hyperactivity disorder (adhd). method: sixty four subjects (45 boys and 15 girls) aged 5-13 who were diagnosed with adhd based on (dsm-iv-tr) criteria were selected for this study. the subjects were randomly assigned to two groups: ...

For parents with children with Attention Deficit / Hyperactivity Disorder (ADD/ADHD), neurofeedback represents an exciting new alternative to treatment with medication. Powerful psycho-stimulant drugs such as Ritalin have side-effects and do not work on changing the underlying causes of the condition. Neurofeedback therapy focuses on changing the underlying symptoms by re-training the brain. Ne...

OBJECTIVE There is evidence to show an increase in use of stimulant substances among university students. This study is a qualitative assessment of the existing situation and the underlying reasons for stimulant use among the students of Tehran University of Medical Sciences in 2006. METHODS Three qualitative methods have been used: focus group discussions with 7 groups (60 individuals) consi...

BACKGROUND The neural consequences of early-life exposure to methylphenidate (MPH; Ritalin) are of great interest given the widespread, and sometimes inappropriate, use in children. Here we examine the impact of juvenile MPH exposure on adult hippocampal neurogenesis. METHODS Rats received MPH (2.0 mg/kg, intraperitoneal, twice daily) or saline (SAL) during preadolescence (postnatal days 20-3...

Objectives: Some studies reported a significant improvement in sleep parameters by melatonin therapy in children with ADHD. Utilizing risperidone along with stimulants is another pharmacologic approach for ADHD treatment. In this study we investigated the effect of melatonin and risperidone on sleep disorders in children with ADHD and compared their effectiveness as well. Methods & Methods: 29 ...

Final data summaries are available for the five remaining chemicals (lovastatin, methylphenidate and its hydrochloride (Ritalin), phenelzine and its acid salts, styrene, and tetrachlorvinphos) out of the 60 chemicals under consideration for carcinogenicity evaluation (Batch #3). Batch #3 chemicals were selected for prioritization from Category I of the tracking database by the process described...

As part of a program to develop medications which can block the binding of cocaine to the dopamine transporter, yet spare dopamine uptake, a series of aromatic ring-substituted methylphenidate derivatives was synthesized and tested for inhibitory potency in [3H]WIN 35,428 binding and [3H]dopamine uptake assays using rat striatal tissue. Synthesis was accomplished by alkylation of 2-bromopyridin...