The aim of this study was to investigate the effect of ketamine and midazolam on preventing the development of morphine tolerance and dependence and withdrawal syndrome in mice. In the present study different groups of mice were received morphine (50 mg/kg, s.c.), morphine (50 mg/kg, s.c.) + ketamine (25, 50, 75 mg/kg, i.p.) , morphine (50 mg/kg , s.c.) + midazolam (0.5, 1, 2 mg/kg, i.p.) , mor...

particle size, board density and adhesive content are the most important factors, influencing on physical and mechanical properties of particleboard. in this study the effects of density, adhesive content and particle size on withdrawal strength of particleboard made from populus (populus alba) particles have been studied. three levels of density including 0.65, 0.7, and 0.75 g/cm3, three level...

Preliminary evidence suggests that there is minimal withdrawal after the cessation of chronically administered buprenorphine and that opioid withdrawal symptoms are delayed compared with those of other opioids. The present study compared the time course and magnitude of buprenorphine withdrawal with a prototypical μ-opioid agonist, morphine. Healthy, out-of-treatment opioid-dependent residentia...

In the present paper, time dependent creep behavior of hollow circular rotating cylinders made of exponentially graded material (EGM) is investigated. Loading is composed of an internal pressure, a distributed temperature field due to steady state heat conduction with convective boundary condition and a centrifugal body force. All the material properties are assumed to be exponentially graded a...

Radiative-convective equilibrium (RCE), in which the radiative cooling in the atmosphere is balanced by the convective heating in a horizontally homogeneous environment, is a good starting point for studying tropical convection. It also provides an idealized framework to compare analogous simulations by global climate models (GCMs) which rely on convective parameterizations, and cloud-resolving...

Recently friction stir welding for manufacturing of welded tubes has been developed. Friction stir welding is a continuous solid state welding process in which a non-consumable rotating tool using severe plastic deformation Can join materials can be join materials. Commonly, a portion of a specially shaped rotating tool is plunged between metalsjoint cross section and adjacent faces of the join...

In this article, the magneto-thermo-elastic problem of exponentially graded material (EGM) hollow rotating disk placed in uniform magnetic and temperature fields is considered. Exact solutions for stresses and perturbations of the magnetic field vector in EGM hollow rotating disk are determined using the infinitesimal theory of magneto-thermo-elasticity under plane stress. The material properti...

Alcohol withdrawal syndrome is characterized by hyperactivity of the nervous system. This hyperactivity represents the brain's attempt to function normally despite the inhibitory effect of chronic alcohol consumption. The syndrome manifests when alcohol consumption ceases. Experimental, clinical, and genetic research have linked the development of withdrawal to alterations in the sensitivity of...

BACKGROUND Nicotine withdrawal is associated with failed smoking cessation and thus contributes to continuance of the habit and increases risk of smoking-related illnesses. Withdrawal is also associated with psychiatric disorders such as depression and alcoholism. However, relatively little is known about how to characterize the severity of withdrawal, including whether withdrawal subtypes exis...