TOPIC: Sleep Disorders TYPE: Original Investigations PURPOSE: To assess possible relationships between Obstructive Apnea (OSA) syndrome and Gluthatione (GSH) redox system: Glutathione Peroxidase1 (GPx1) Reductase (GSSG-Red). OSA is characterized by sleep fragmentation, repetitive episodes of hypoxia/reoxygenation, systemic glymphatic activity lipid dysregulation, increasing oxidative stress wit...

Background: Clinically relevant anti-carbamylated (anti-CarP) antibodies are detected in up to 45% of rheumatoid arthritis (RA) patients and associated with severe radiological progression, higher disease activity, significantly more disability when studied early phases arthritis. Objectives: We aimed determine the prevalence anti-CarP Mexican Hispanics established RA assess their relationship ...

Contact address: Edme Roxana Mustafa, Department 3 Cardiology, University of Medicine and Pharmacy Craiova, Romania. E-mail: [email protected] 1 Department 3 of Cardiology, University of Medicine and Pharmacy, Craiova, Romania 2 Department of Thoracic Surgery, University of Medicine and Pharmacy, Craiova, Romania 3 Department of Pathology, Emergency Hospital Craiova, Romania A 58 year old m...

Background Circulating bioactive lipids can provide information about the pathogenesis of specific diseases and potentially help predict therapeutic response. Choosing right biological therapy earlier in course rheumatoid arthritis (RA) could reach goal remission. Objectives We hypothesized that circulating at baseline would identify metabolic profiles patient response to define elements pathob...

it is now generally accepted that the rise of the genre of novel required a kind of worldview as well as a philosophical theory of man which had not been in existence until recent centuries, after severe changes which resulted into modern civilization. novel and realistic novel in particular, is a genre dealing with individual man and his possibilities in facing with problems and issues of the ...

O riginally characterized as “globules of his blood” in 1675 by the Dutch microscopist van Leeuwenhoek, the crucial role of erythrocytes, or red blood cells, in regulating normal human physiology was not appreciated until centuries later. In contemporary medical taxonomy, the construct of anemia equates to a reduction in red blood cell mass and the diagnosis is established using convenient sex-...

in 1902, well known archibald garrod applied mendels gene concept to human characters. he opened a new window in understanding the etiology of metabolic disorders. he proposed biochemical changes as the etiology of metabolic disorders in his series of papers inborn errors of metabolism (1906). after establishing prenatal diagnosis facilities for the detection of chromosomal abnormalities in our...

The family Arecaceae is broadly distributed in Cuba, where around 97 species of palms are found, 90 % of them are endemic. Fruit extracts of some palms have shown to be effective in different experimental models, such as prostatic hyperplasia. In additions they have demonstrated anti-inflammatory, analgesic, immunomodulating, healing, antithrombotic, vasodilator; antioxidant and hypoglycemic ef...

At the current time, causal factors for ulcerative colitis and Crohn’s disease are unknown. Still, there is strong evidence to suggest that genetic predisposition plasy a major role in the development of IBD. The purpose of this review is to highlight the important genetic aspects of IBD. Keywords— DNA methylation, genomics, ulcerative colitis and Crohn’s disease I. DNA METHYLATION IN INFLAMMAT...

I propose a restricted theory of tone-TBU association called Basic Tonal Theory (BTT). BTT includes six well-attested constraints, and a restricted GEN. The typology contains attested cases of tone overcrowding resolution such as tone deletion, mora epenthesis, and mora deletion, but also predicts unattested cases of languages that resolve tonal crowding by using a combination of the aforementi...